The Southeast Resource Center for Integrated Metabolomics (SECIM) integrates existing strengths to create a comprehensive resource for basic and clinical scientists to obtain state-of-the-art metabolomics data and analyses. The SECIM Promotion and Outreach (P&O) Core is co-directed by Dr. Steven Smith, a clinical investigator and Scientific Director ofthe Sanford-Burnham Translational Research Institute in Orlando, and Dr. Michael Conlon, Chief Operating Officer of the UF CTSI and PI of VIVO, a system for scholarly networking and discovery. P&O is responsible for connecting users to SECIM services and science, and it has established several aims to accomplish this goal. P&O will establish the SECIM brand by establishing web-based and social media outreach, building new institutional collaborations and a larger user base, and ensuring that SECIM is represented at major meetings and conferences. P&O will coordinate educational activities that will train new users in the analytical tools and analysis offered by SECIM. This will include the development of online educational resources as well as the annual SECIM Metabolomics Workshop, which will include general introductions to technologies as well as more focused offerings for specific groups, such as bioinformatics for biologists or clinicians. These workshops represent a critical interface between SECIM analytical cores, bioinformatics, and users. Pilot &Feasibility (P&F) projects will be administered through the P&O Core, which will capture all metrics such as publications, meeting presentations, new grants, etc., for both P&F projects and general SECIM users. The funds available for P&F projects are significantly enhanced through matching funds from several groups at UF, allowing more studies to be done through SECIM in the early years of growth. The P&F projects are a core component ofthe SECIM business model, as described in the Administrative Core. P&O will help to connect the network of SECIM users to enhance the biomedical impact of metabolomics research.

Public Health Relevance

The major goal of metabolomics is the measurement and characterization of metabolites from living organisms, including people. Small molecule metabolites are sensitive to disease, treatment, and many environmental factors, and they can be used as indicators of disease in diagnosis or as markers to assess the outcome of treatment.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Resource-Related Research Projects--Cooperative Agreements (U24)
Project #
1U24DK097209-01A1
Application #
8694159
Study Section
Special Emphasis Panel (ZRG1-BST-F (50))
Project Start
Project End
Budget Start
2013-09-11
Budget End
2014-08-31
Support Year
1
Fiscal Year
2013
Total Cost
$222,593
Indirect Cost
$64,924
Name
University of Florida
Department
Type
DUNS #
969663814
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Brouwers, Bram; Stephens, Natalie A; Costford, Sheila R et al. (2018) Elevated Nicotinamide Phosphoribosyl Transferase in Skeletal Muscle Augments Exercise Performance and Mitochondrial Respiratory Capacity Following Exercise Training. Front Physiol 9:704
Zhao, Qi; Shen, Hui; Su, Kuan-Jui et al. (2018) Metabolomic profiles associated with bone mineral density in US Caucasian women. Nutr Metab (Lond) 15:57
von Morze, Cornelius; Merritt, Matthew E (2018) Cancer in the crosshairs: targeting cancer metabolism with hyperpolarized carbon-13 MRI technology. NMR Biomed :e3937
Kirpich, Alexander S; Ibarra, Miguel; Moskalenko, Oleksandr et al. (2018) SECIMTools: a suite of metabolomics data analysis tools. BMC Bioinformatics 19:151
Verhoeven, Koen J F; Verbon, Eline H; van Gurp, Thomas P et al. (2018) Intergenerational environmental effects: functional signals in offspring transcriptomes and metabolomes after parental jasmonic acid treatment in apomictic dandelion. New Phytol 217:871-882
Walejko, Jacquelyn M; Kim, Seungbum; Goel, Ruby et al. (2018) Gut microbiota and serum metabolite differences in African Americans and White Americans with high blood pressure. Int J Cardiol 271:336-339
Walejko, Jacquelyn M; Koelmel, Jeremy P; Garrett, Timothy J et al. (2018) Multi-omics Approach Reveals Metabolic Changes in the Heart at Birth. Am J Physiol Endocrinol Metab :
Wu, Cheng-Yang; Satapati, Santhosh; Gui, Wenjun et al. (2018) A novel inhibitor of pyruvate dehydrogenase kinase stimulates myocardial carbohydrate oxidation in diet-induced obesity. J Biol Chem 293:9604-9613
Chouinard, Christopher D; Cruzeiro, Vinicius Wilian D; Kemperman, Robin H J et al. (2018) Cation-Dependent Conformations in 25-Hydroxyvitamin D3-Cation Adducts Measured by Ion Mobility-Mass Spectrometry and Theoretical Modeling. Int J Mass Spectrom 432:1-8
Sirusi, Ali A; Suh, Eul Hyun; Kovacs, Zoltan et al. (2018) The effect of Ho3+ doping on 13C dynamic nuclear polarization at 5 T. Phys Chem Chem Phys 20:728-731

Showing the most recent 10 out of 71 publications