This Biocomputing and Bioinformatics Core (BBC) will have four main functions: (1) to support all CCNE projects in biomarker analysis and database mining;(2) to process, analyze, and interpret nanoparticle imaging data of both cancer cells and tissue specimens;(3) to develop a high-speed biocomputing infrastructure for information processing, management, and data sharing within the CCNE;and (4) to interface with the NCI Cancer Biomedical Informatics Grid (CaBIG), and to share data and tools with other CCNE centers and with the broader scientific community. This Core builds on the biocomputing strengths in the joint Emory/Georgia Tech Department of Biomedical Engineering, especially the translational cancer bioinformatics and bioimaging facilities of the Medical Informatics and Bioimaging Lab (MIB Lab) under the direction of Dr. M. Wang.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Specialized Center--Cooperative Agreements (U54)
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Special Emphasis Panel (ZCA1)
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Emory University
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Lee, Kate Y J; Lee, Gee Young; Lane, Lucas A et al. (2017) Functionalized, Long-Circulating, and Ultrasmall Gold Nanocarriers for Overcoming the Barriers of Low Nanoparticle Delivery Efficiency and Poor Tumor Penetration. Bioconjug Chem 28:244-252
Kaddi, Chanchala D; Wang, May D (2017) Models for Predicting Stage in Head and Neck Squamous Cell Carcinoma Using Proteomic and Transcriptomic Data. IEEE J Biomed Health Inform 21:246-253
Tong, Li; Yang, Cheng; Wu, Po-Yen et al. (2016) Evaluating the impact of sequencing error correction for RNA-seq data with ERCC RNA spike-in controls. IEEE EMBS Int Conf Biomed Health Inform 2016:74-77
Phan, John H; Hoffman, Ryan; Kothari, Sonal et al. (2016) Integration of Multi-Modal Biomedical Data to Predict Cancer Grade and Patient Survival. IEEE EMBS Int Conf Biomed Health Inform 2016:577-580
Wu, Po-Yen; Wang, May D (2016) The Selection of Quantification Pipelines for Illumina RNA-seq Data Using a Subsampling Approach. IEEE EMBS Int Conf Biomed Health Inform 2016:78-81
Raharjo, I; Burns, T G; Venugopalan, J et al. (2016) Development of user-friendly and interactive data collection system for cerebral palsy. IEEE EMBS Int Conf Biomed Health Inform 2016:406-409
Kothari, Sonal; Wu, Hang; Tong, Li et al. (2016) Automated Risk Prediction for Esophageal Optical Endomicroscopic Images. IEEE EMBS Int Conf Biomed Health Inform 2016:160-163
Quan, Li; Wu, Jiangxiao; Lane, Lucas A et al. (2016) Enhanced Detection Specificity and Sensitivity of Alzheimer's Disease Using Amyloid-?-Targeted Quantum Dots. Bioconjug Chem 27:809-14
Mishra, Sameer; Kaddi, Chanchala D; Wang, May D (2016) Pan-cancer analysis for studying cancer stage using protein and gene expression data. Conf Proc IEEE Eng Med Biol Soc 2016:2440-2443
Pethiyagoda, Theruni; Chanani, Nikhil; Cheng, Chihwen et al. (2016) PEPCOR - A Risk Prediction Model for Pediatric Intensive Care Units Utilizing Ventilator Days and Length of Stay. IEEE EMBS Int Conf Biomed Health Inform 2016:86-89

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