Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA143906-04
Application #
8555265
Study Section
Special Emphasis Panel (ZCA1-SRLB-9 (O1))
Project Start
2009-09-30
Project End
2014-08-31
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
4
Fiscal Year
2012
Total Cost
$500,061
Indirect Cost
$173,338
Name
Scripps Research Institute
Department
Type
DUNS #
781613492
City
La Jolla
State
CA
Country
United States
Zip Code
92037
West, Jeffrey; Newton, Paul K (2017) Chemotherapeutic Dose Scheduling Based on Tumor Growth Rates Provides a Case for Low-Dose Metronomic High-Entropy Therapies. Cancer Res 77:6717-6728
Kuhn, P; Keating, S M; Baxter, G T et al. (2017) Lessons Learned: Transfer of the High-Definition Circulating Tumor Cell Assay Platform to Development as a Commercialized Clinical Assay Platform. Clin Pharmacol Ther 102:777-785
Carlsson, Anders; Kuhn, Peter; Luttgen, Madelyn S et al. (2017) Paired High-Content Analysis of Prostate Cancer Cells in Bone Marrow and Blood Characterizes Increased Androgen Receptor Expression in Tumor Cell Clusters. Clin Cancer Res 23:1722-1732
West, Jeffrey; Hasnain, Zaki; Mason, Jeremy et al. (2016) The prisoner's dilemma as a cancer model. Converg Sci Phys Oncol 2:
West, Jeffrey; Hasnain, Zaki; Macklin, Paul et al. (2016) AN EVOLUTIONARY MODEL OF TUMOR CELL KINETICS AND THE EMERGENCE OF MOLECULAR HETEROGENEITY DRIVING GOMPERTZIAN GROWTH. SIAM Rev Soc Ind Appl Math 58:716-736
Mitrugno, Annachiara; Tormoen, Garth W; Kuhn, Peter et al. (2016) The prothrombotic activity of cancer cells in the circulation. Blood Rev 30:11-9
Baker-Groberg, Sandra M; Phillips, Kevin G; Healy, Laura D et al. (2015) Critical behavior of subcellular density organization during neutrophil activation and migration. Cell Mol Bioeng 8:543-552
Phillips, Kevin G; Lee, Angela M; Tormoen, Garth W et al. (2015) The thrombotic potential of circulating tumor microemboli: computational modeling of circulating tumor cell-induced coagulation. Am J Physiol Cell Physiol 308:C229-36
King, Michael R; Phillips, Kevin G; Mitrugno, Annachiara et al. (2015) A physical sciences network characterization of circulating tumor cell aggregate transport. Am J Physiol Cell Physiol 308:C792-802
Ruiz, Carmen; Li, Julia; Luttgen, Madelyn S et al. (2015) Limited genomic heterogeneity of circulating melanoma cells in advanced stage patients. Phys Biol 12:016008

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