The Program for the Elimination of Cancer Disparities (PECaD) at the Alvin J. Siteman Cancer Center, St Louis, MO of Washington University School of Medicine and Barnes-Jewish Hospital was established in 2003 with institutional funds in response to known excess cancer burden within the region particularly for minority and medically underserved populations. The Goals are to create a national model for eliminating disparities In cancer through community-based partnerships and community based participatory research (CBPR);to increase access by breaking down barriers to quality cancer care;and to be a catalyst for change in our region by fostering healthy communities. Given the fractured history of St Louis and its segregation, PECaD has worked with numerous community organizations and provider groups to build trust and has harnessed resources from non federal sources and NCI. We now propose to further strengthen partnerships in the St. Louis region and extend our activities to additional areas chosen based on poverty levels;limited access to cancer screening and prevention services;excess cancer incidence or mortality;and expressed community Interest In collaborative efforts to address cancer health disparities. Our three communities are St Louis City and North County, MO;St. Clair County, IL, and southeastern Missouri.
The Specific aims are: 1. In collaboration with our community partners, using the community outreach program and working with our community partnerships, we will extend and evaluate the effectiveness of outreach. 2. In a research project created in partnership with our colorectal cancer community partnership, we will design and conduct a RCT of community awareness plus systems level changes to reinforce provider behavior change to order and follow-up on colorectal cancer screening tests. 3. In our pilot educational research project created with our prostate cancer community partnership, we will evaluate barriers and facilitators to participation in prostate CA tissue collection for research (biobanking). 4. Through our training program, provide CBPR training for researchers and community members collaborating with the program and institute an ongoing process for Identifying and vetting future pilot projects. 5. In conjunction with our community Disparities Elimination Advisory Committee (DEAC), we will develop a framework for evaluation within and across our Community Outreach, Research, and Training Programs.

Public Health Relevance

Excess cancer mortality In low income, minority and underserved populations will be addressed through community based participatory research projects that bring prevention information and access to 3 high risk populations. In addition a research project addressing disparities in access to colorectal cancer screening will be Implemented and evaluated along with education and training program s to Increase expertise among junior investigators addressing cancer health disparities.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Specialized Center--Cooperative Agreements (U54)
Project #
Application #
Study Section
Special Emphasis Panel (ZCA1-PCRB-G (M1))
Program Officer
Banez, Lionel L
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Washington University
Schools of Medicine
Saint Louis
United States
Zip Code
Muenks, Carol E; Sewell, Whitney C; Hogan, Patrick G et al. (2018) Methicillin-Resistant Staphylococcus aureus: The Effects Are More Than Skin Deep. J Pediatr 199:158-165
Warner, Wayne A; Lee, Tammy Y; Fang, Fang et al. (2018) The burden of prostate cancer in Trinidad and Tobago: one of the highest mortality rates in the world. Cancer Causes Control 29:685-697
Gehlert, Sarah; Mozersky, Jessica (2018) Seeing Beyond the Margins: Challenges to Informed Inclusion of Vulnerable Populations in Research. J Law Med Ethics 46:30-43
Khan, Saira; Hicks, Veronica; Rancilio, Danielle et al. (2018) Predictors of Follow-Up Visits Post Radical Prostatectomy. Am J Mens Health 12:760-765
Goodman, Melody S; Sanders Thompson, Vetta L; Johnson, Cassandra Arroyo et al. (2017) EVALUATING COMMUNITY ENGAGEMENT IN RESEARCH: QUANTITATIVE MEASURE DEVELOPMENT. J Community Psychol 45:17-32
Drake, Bettina F; Brown, Katherine M; Gehlert, Sarah et al. (2017) Development of Plain Language Supplemental Materials for the Biobank Informed Consent Process. J Cancer Educ 32:836-844
Drake, Bettina F; Boyd, Danielle; Carter, Kimberly et al. (2017) Barriers and Strategies to Participation in Tissue Research Among African-American Men. J Cancer Educ 32:51-58
Arnold, Lauren D; McGilvray, Martha M; Kyle Cooper, J et al. (2017) Inadequate Cancer Screening: Lack of Provider Continuity is a Greater Obstacle than Medical Mistrust. J Health Care Poor Underserved 28:362-377
Komaie, Goldie; Ekenga, Christine C; Sanders Thompson, Vetta L et al. (2017) Increasing Community Research Capacity to Address Health Disparities. J Empir Res Hum Res Ethics 12:55-66
Colditz, Graham A; Gehlert, Sarah; Bowen, Deborah J et al. (2016) Toward a Modern Science of Obesity at Washington University: How We Do It and What is the Payoff? Cancer Prev Res (Phila) 9:503-8

Showing the most recent 10 out of 64 publications