The theme of our BETRNet Research Center (RC) is to identify genetic determinants of Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC) to enable genetic marker guided early detection, risk stratification, prevention and therapy. The BETRNet Patients Registry-Virtual Biorepository (PRVB) Core will interact with all RC investigators at our participating institutions to continue and improve the effective methods and designs that successfully enabled us to share human biospecimens and clinical data across institutions to efficiently achieve our project goals in our existing BETRNet and will enable success in our new projects. We communicate regularly with our RC investigators to make sure they have access to high quality, clinically annotated biospecimens for their research questions. In addition, the Core provides infrastructure and oversight for secure management of all biospecimen, clinical, demographic and molecular data from the BETRNet RC, working closely with our investigators and the BETRNet Administrative Core. The Core will ensure adherence to data sharing in adherence with the guidelines as outlined from the BETRNet Coordinating Center and the NCI BETRNet Program Office in order to provide biospecimens and data to other BETRNet RCs for research.
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| Codipilly, Don Chamil; Chandar, Apoorva Krishna; Singh, Siddharth et al. (2018) The Effect of Endoscopic Surveillance in Patients With Barrett's Esophagus: A Systematic Review and Meta-analysis. Gastroenterology 154:2068-2086.e5 |
| Evans, Daniel R; Venkitachalam, Srividya; Revoredo, Leslie et al. (2018) Evidence for GALNT12 as a moderate penetrance gene for colorectal cancer. Hum Mutat 39:1092-1101 |
| Chan, M Q; Blum, A E; Chandar, A K et al. (2018) Association of sporadic and familial Barrett's esophagus with breast cancer. Dis Esophagus 31: |
| Yu, Ming; Maden, Sean K; Stachler, Matthew et al. (2018) Subtypes of Barrett's oesophagus and oesophageal adenocarcinoma based on genome-wide methylation analysis. Gut : |
| Berger, Nathan A (2018) New light on the pancreatic cyst conundrum. Transl Cancer Res 7:S545-S548 |
| Berger, Nathan A (2018) Young Adult Cancer: Influence of the Obesity Pandemic. Obesity (Silver Spring) 26:641-650 |
| Moinova, Helen R; LaFramboise, Thomas; Lutterbaugh, James D et al. (2018) Identifying DNA methylation biomarkers for non-endoscopic detection of Barrett's esophagus. Sci Transl Med 10: |
| Stachler, Matthew D; Camarda, Nicholas D; Deitrick, Christopher et al. (2018) Detection of Mutations in Barrett's Esophagus Before Progression to High-Grade Dysplasia or Adenocarcinoma. Gastroenterology 155:156-167 |
| Venkitachalam, Srividya; Guda, Kishore (2017) Altered glycosyltransferases in colorectal cancer. Expert Rev Gastroenterol Hepatol 11:5-7 |
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