- 5 U54 EB005149-05S3 This is an application for a 1-year, administrative supplement to 5U54EB005149 (National Alliance for Medical Image Computing), in response to NOT-OD-09-056. The goal of this project is to strenghten the components of the open-source NA-MIC kit for supporting basic science. If funded, the project will result in the retention of 1.0 FTE position for an engineer in Massachusetts. Additional jobs will also be preserved through expenditures from overhead. The open-source nature of NA-MIC software tools and their multi-level expandability, combined with concerted outreach and training efforts, have encouraged external researchers to use NA-MIC technology for a variety of new biomedical research topics. Many such uses were not expected or envisioned at the time of the original submission. Based on our experience, we have identified one key area that requires technological improvements that will benefit both the core activities of NA-MIC as well as these more novel uses of the technology. This proposal will strengthen the offerings provided by the NA-MIC Kit for basic science research as follows: 1) Improve the stability and quality of Slicer 3 by increasing Quality Assurance (QA) engineering to keep up with increased development. 2) Improve our outreach and education efforts through expansion of our tutorial and training materials.

Public Health Relevance

: NIH-funded research in brain imaging has generated many image analysis tools that can be applied to other regions of the human body. Improved testing and training materials for these medical imaging visualization and analysis open source tools, will 1) preserve a highly-skilled job and 2) lower the barrier for scientists with limited local resources to access and take advantage of this valuable software.

National Institute of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Specialized Center--Cooperative Agreements (U54)
Project #
Application #
Study Section
Special Emphasis Panel (ZRG1-BST-A (55))
Program Officer
Pai, Vinay Manjunath
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Brigham and Women's Hospital
United States
Zip Code
Ghayoor, Ali; Vaidya, Jatin G; Johnson, Hans J (2018) Robust automated constellation-based landmark detection in human brain imaging. Neuroimage 170:471-481
Wachinger, Christian; Toews, Matthew; Langs, Georg et al. (2018) Keypoint Transfer for Fast Whole-Body Segmentation. IEEE Trans Med Imaging :
Lyu, Ilwoo; Perdomo, Jonathan; Yapuncich, Gabriel S et al. (2018) Group-wise Shape Correspondence of Variable and Complex Objects. Proc SPIE Int Soc Opt Eng 10574:
Hong, Sungmin; Fishbaugh, James; Gerig, Guido (2018) 4D CONTINUOUS MEDIAL REPRESENTATION BY GEODESIC SHAPE REGRESSION. Proc IEEE Int Symp Biomed Imaging 2018:1014-1017
Swanson, Meghan R; Wolff, Jason J; Shen, Mark D et al. (2018) Development of White Matter Circuitry in Infants With Fragile X Syndrome. JAMA Psychiatry 75:505-513
Swanson, Meghan R; Shen, Mark D; Wolff, Jason J et al. (2018) Naturalistic Language Recordings Reveal ""Hypervocal"" Infants at High Familial Risk for Autism. Child Dev 89:e60-e73
Swanson, Meghan R; Shen, Mark D; Wolff, Jason J et al. (2017) Subcortical Brain and Behavior Phenotypes Differentiate Infants With Autism Versus Language Delay. Biol Psychiatry Cogn Neurosci Neuroimaging 2:664-672
Veni, Gopalkrishna; Elhabian, Shireen Y; Whitaker, Ross T (2017) ShapeCut: Bayesian surface estimation using shape-driven graph. Med Image Anal 40:11-29
Irimia, Andrei; Goh, Sheng-Yang Matthew; Wade, Adam C et al. (2017) Traumatic Brain Injury Severity, Neuropathophysiology, and Clinical Outcome: Insights from Multimodal Neuroimaging. Front Neurol 8:530
Rutherford, Helena J V; Maupin, Angela N; Landi, Nicole et al. (2017) Parental reflective functioning and the neural correlates of processing infant affective cues. Soc Neurosci 12:519-529

Showing the most recent 10 out of 668 publications