Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54GM074946-05
Application #
7667967
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2009-07-01
Budget End
2010-06-30
Support Year
5
Fiscal Year
2008
Total Cost
$660,777
Indirect Cost
Name
Los Alamos National Lab
Department
Type
DUNS #
175252894
City
Los Alamos
State
NM
Country
United States
Zip Code
87545
Li, Qufei; Shen, Rong; Treger, Jeremy S et al. (2015) Resting state of the human proton channel dimer in a lipid bilayer. Proc Natl Acad Sci U S A 112:E5926-35
Li, Qufei; Wanderling, Sherry; Paduch, Marcin et al. (2014) Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain. Nat Struct Mol Biol 21:244-52
Li, Qufei; Wanderling, Sherry; Sompornpisut, Pornthep et al. (2014) Structural basis of lipid-driven conformational transitions in the KvAP voltage-sensing domain. Nat Struct Mol Biol 21:160-6
Cabantous, St├ęphanie; Nguyen, Hau B; Pedelacq, Jean-Denis et al. (2013) A new protein-protein interaction sensor based on tripartite split-GFP association. Sci Rep 3:2854
Shukla, Arun K; Manglik, Aashish; Kruse, Andrew C et al. (2013) Structure of active ?-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide. Nature 497:137-41
Paduch, Marcin; Koide, Akiko; Uysal, Serdar et al. (2013) Generating conformation-specific synthetic antibodies to trap proteins in selected functional states. Methods 60:3-14
Nguyen, Hau B; Hung, Li-Wei; Yeates, Todd O et al. (2013) Split green fluorescent protein as a modular binding partner for protein crystallization. Acta Crystallogr D Biol Crystallogr 69:2513-23
Kim, Heungbok; Webster, Cecelia; Roberts, Justin K M et al. (2012) Enhancement of crystallization with nucleotide ligands identified by dye-ligand affinity chromatography. J Struct Funct Genomics 13:71-9
Ru, Heng; Zhao, Lixia; Ding, Wei et al. (2012) S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS. Acta Crystallogr D Biol Crystallogr 68:521-30
Li, Qufei; Jogini, Vishwanath; Wanderling, Sherry et al. (2012) Expression, purification, and reconstitution of the voltage-sensing domain from Ci-VSP. Biochemistry 51:8132-42

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