The success of the Center for Reproductive Research (CRR) at Northwestern University is determined by the skills of the participating investigators, their commitment to the project and the overall objectives of the program, and the robustness of the Administrative Core in organizing research activities. The CRR at Northwestern University will include one core unit in addition to the four research projects. The Administrative Core provides a centralized administrative structure to facilitate the needs and the activities of the four research projects that comprise the Center. The Administrative Core organizes, supports, and provides governance and communication to the four research projects. The Core functions to encourage research, solve problems, and maintain documents and budgets. The Administrative Core serves the research projects and makes every effort to ensure that administrative barriers do not interrupt the flow of intellectual energy. The Administrative Core provides uniform and centralized administration, accounting and purchasing services to the Center participants, arranges the quarterly educational and business Center meetings, coordinates visits of expert consultants, and facilitates the Annual Advisory Board Meeting. The Administrative Core is responsible for all regulatory and compliance issues, including all program-related Animal Care and Usage Committee (ACUC) documenation and Institutional Review Board (IRB) submissions. The Program Coordinator is also the webmaster for the Center and keeps the CRR Web site current with scientific, community and school outreach events. The Administrative Core will be used by all projects in the Center with equal distribution. Decisions regarding access to administrative and accounting services will be made by the Program Coordinator in consultation with the Director. The Administrative Core will be directed by Teresa K. Woodruff, PhD, Thomas J. Watkins Professor of Obstetrics and Gynecology. The Administrative Core will be administered by the Program Coordinator, Barbara Gushing, BBA. Barbara implements program policies and devises strategies for efficient office management, and interaction with NIH personnel. She is thoroughly familiar with the internal and external regulations concerning grant management. The Program Coordinator, in consultation with the Director, will oversee the day-to-day management of the various activities that are generated by the four research project.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Specialized Center--Cooperative Agreements (U54)
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Special Emphasis Panel (ZHD1-DSR-L)
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Northwestern University at Chicago
United States
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Skory, Robin M; Xu, Yuanming; Shea, Lonnie D et al. (2015) Engineering the ovarian cycle using in vitro follicle culture. Hum Reprod 30:1386-95
Wood, Charles D; Vijayvergia, Mayank; Miller, Frank H et al. (2015) Multi-modal magnetic resonance elastography for noninvasive assessment of ovarian tissue rigidity in vivo. Acta Biomater 13:295-300
Hornick, Jessica E; Duncan, Francesca E; Sun, Mingxuan et al. (2015) Age-associated alterations in the micromechanical properties of chromosomes in the mammalian egg. J Assist Reprod Genet 32:765-9
Jiao, Ze-Xu; Xu, Min; Woodruff, Teresa K (2014) Age-related increase in aneuploidy and alteration of gene expression in mouse first polar bodies. J Assist Reprod Genet 31:731-7
Shea, Lonnie D; Woodruff, Teresa K; Shikanov, Ariella (2014) Bioengineering the ovarian follicle microenvironment. Annu Rev Biomed Eng 16:29-52
Duncan, Francesca E; Derman, Benjamin; Woodruff, Teresa K (2014) A small field for fertile science: the low visibility of reproductive science in high impact journals. J Assist Reprod Genet 31:511-20
Tagler, David; Makanji, Yogeshwar; Tu, Tao et al. (2014) Promoting extracellular matrix remodeling via ascorbic acid enhances the survival of primary ovarian follicles encapsulated in alginate hydrogels. Biotechnol Bioeng 111:1417-29
Mutharasan, Priscilla; Galdones, Eugene; Peñalver Bernabé, Beatriz et al. (2013) Evidence for chromosome 2p16.3 polycystic ovary syndrome susceptibility locus in affected women of European ancestry. J Clin Endocrinol Metab 98:E185-90
Jiao, Ze-Xu; Woodruff, Teresa K (2013) Detection and quantification of maternal-effect gene transcripts in mouse second polar bodies: potential markers of embryo developmental competence. Fertil Steril 99:2055-61
Tagler, David; Makanji, Yogeshwar; Anderson, Nicholas R et al. (2013) Supplemented ?MEM/F12-based medium enables the survival and growth of primary ovarian follicles encapsulated in alginate hydrogels. Biotechnol Bioeng 110:3258-68

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