Abstract

CORE C. ADMINISTRATION AND MANAGEMENT A.
Specific Aims The goals of this core are to facilitate the scientific mission of the center in a way that is maximally responsive to the needs of our research and technical personnel.
Its specific aims are: 1. Provide administrative coordination of the overall research effort. 2. Facilitate interactions with MLPCN staff and investigators. 3. Manage budget and personnel issues related to the KU CMLD center.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Human Genome Research Institute (NHGRI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54HG005031-05
Application #
8379498
Study Section
Special Emphasis Panel (ZRG1-IFCN-K)
Project Start
Project End
Budget Start
2012-06-01
Budget End
2013-05-31
Support Year
5
Fiscal Year
2012
Total Cost
$260,405
Indirect Cost
$83,259

  Institution

Name
University of Kansas Lawrence
Department
Type
DUNS #
076248616
City
Lawrence
State
KS
Country
United States
Zip Code
66045

  Publications

Frankowski, Kevin J; Wang, Chen; Patnaik, Samarjit et al. (2018) Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis. Sci Transl Med 10:
Luderman, Kathryn D; Conroy, Jennie L; Free, R Benjamin et al. (2018) Identification of Positive Allosteric Modulators of the D1 Dopamine Receptor That Act at Diverse Binding Sites. Mol Pharmacol 94:1197-1209
Swingle, Mark; Volmar, Claude-Henry; Saldanha, S Adrian et al. (2017) An Ultra-High-Throughput Screen for Catalytic Inhibitors of Serine/Threonine Protein Phosphatases Types 1 and 5 (PP1C and PP5C). SLAS Discov 22:21-31
Hackler, Amber; Patrick, Stephen L; Kahney, Elizabeth W et al. (2017) Antiparasitic lethality of sulfonamidebenzamides in kinetoplastids. Bioorg Med Chem Lett 27:755-758
He, Shanshan; Li, Kelin; Lin, Billy et al. (2017) Development of an Aryloxazole Class of Hepatitis C Virus Inhibitors Targeting the Entry Stage of the Viral Replication Cycle. J Med Chem 60:6364-6383
Skarsfeldt, Mark A; Jepps, Thomas A; Bomholtz, Sofia H et al. (2016) pH-dependent inhibition of K?P3.1 prolongs atrial refractoriness in whole hearts. Pflugers Arch 468:643-54
Chattopadhyay, Debasish; Swingle, Mark R; Salter, Edward A et al. (2016) Crystal structures and mutagenesis of PPP-family ser/thr protein phosphatases elucidate the selectivity of cantharidin and novel norcantharidin-based inhibitors of PP5C. Biochem Pharmacol 109:14-26
Kuramoto, Kenta; Wang, Nan; Fan, Yuying et al. (2016) Autophagy activation by novel inducers prevents BECN2-mediated drug tolerance to cannabinoids. Autophagy 12:1460-71
Chung, Dong-Hoon; Golden, Jennifer E; Adcock, Robert S et al. (2016) Discovery of a Broad-Spectrum Antiviral Compound That Inhibits Pyrimidine Biosynthesis and Establishes a Type 1 Interferon-Independent Antiviral State. Antimicrob Agents Chemother 60:4552-62
Aflaki, Elma; Borger, Daniel K; Moaven, Nima et al. (2016) A New Glucocerebrosidase Chaperone Reduces ?-Synuclein and Glycolipid Levels in iPSC-Derived Dopaminergic Neurons from Patients with Gaucher Disease and Parkinsonism. J Neurosci 36:7441-52

Showing the most recent 10 out of 51 publications