The support services for clinical research are described together because they share resourcesand personnel and operate in an integrated manner to achieve common objectives.Clinical research at CHOP will be organized largely through the Clinical Core. This Core provides.the infrastructure for patient management enabling the recruitment of subjects for specific projectsin particular, the inter-Center collaborative clinical studies. The Clinical Core is staffed byhematologists, research nurses, social worker, psychologist, psychiatrist, genetic counselor, datacoordinator, and administrative support staff. They will be responsible for education, recruitment,and enrollment of study subjects. In addition, they will coordinate the scheduling of subject visits,clinical monitoring of study subjects, data collection, communication with the Statistical and DataManagement Center, and all other required procedures to enable the smooth conduct of approvedclinical studies.Several members of the Clinical Core staff will also serve the patient care Services Core of theCenter. These activities will include the Educational, Diagnostic, counseling, and CommunityOutreach programs of the Center. In many cases these services will be performed in collaborationwith other services available in the home institution or in the community. The Center will continueto offer its regional and national Professional (Continuing) Education program at the major nationalsickle cell conferences.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Specialized Center--Cooperative Agreements (U54)
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Special Emphasis Panel (ZHL1-CSR-F (S1))
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Children's Hospital of Philadelphia
United States
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Dougherty, Kelly A; Schall, Joan I; Kawchak, Deborah A et al. (2012) No improvement in suboptimal vitamin A status with a randomized, double-blind, placebo-controlled trial of vitamin A supplementation in children with sickle cell disease. Am J Clin Nutr 96:932-40
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