Evolution. Nuclear Overhauser enhancement NMR studies of the hydrogen-bonded complex between cytosine and serine-containing peptides are currently underway to definitively establish the proper formulation of the hydrogen-bonded structure. Protein Synthesis. Experimental dissection and elucidation of the mechanism of the reductive activation of yeast valyl-tRNA synthetase is continuing. A lipophilic substance found in 15-fold higher concentrations in rapidly growing than in resting yeast cells has been identified as a dioctylphthalate. The possibility of its having an activator role in protein biosynthesis is being studied.

Project Start
Project End
Budget Start
Budget End
Support Year
27
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Arthritis, Diabetes, Digestive & Kid Dis
Department
Type
DUNS #
City
State
Country
United States
Zip Code