A mouse model of selenium-vitamin E deficiency was developed in which the deficiency disease was potentiated by the addition of silver acetate to the basal diet. Of 3 strains of mice tested for relative susceptibility the C57BL strain was found to be most satisfactory in terms of producing myocardial lesions.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Intramural Research (Z01)
Project #
1Z01HL005216-01
Application #
3858173
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1991
Total Cost
Indirect Cost
Name
National Heart, Lung, and Blood Institute
Department
Type
DUNS #
City
State
Country
United States
Zip Code