We are collaborating with Serguei Kozlov (Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, NCI, Frederick, MD) and Christine Alewine (LMB) to determine if mesothelin is needed for pancreatic cancer development or progression. To do this KPC mice, which develop pancreatic cancers, have been crossed with mesothelin -/- mice. KPC mice not making mesothelin have been obtained and are being followed for development of pancreatic cancer. If cancer develops we will then determine how long the mice live and if the cancer spreads.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Investigator-Initiated Intramural Research Projects (ZIA)
Project #
1ZIABC010298-20
Application #
9556254
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
20
Fiscal Year
2017
Total Cost
Indirect Cost
Name
Basic Sciences
Department
Type
DUNS #
City
State
Country
Zip Code
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