1. We completed analysis of the main case-control study and published approximately 50 reports in peer-reviewed journals. 2. We demonstrated that the patterns of risk vary according to the subtype of lymphoma. 3. We showed that genetic risk factors for occurrance of NHL also predicted survival;We're continuing to explore other subtypes to compare the patterns of etiology and survival. 4. To conduct a GWAS and to study the genetic polymorphism with more power, we are pooling data within Interlymph. 5. We continued to collaborate with InterLymph and we reported on the pooled estimates for overweight, sunlight, hepatitis C virus, hair dyes, and reproductive history. 6. We combined environmental data from other sources with study data to continue to investigate environmental risks. This work is ongoing.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Investigator-Initiated Intramural Research Projects (ZIA)
Project #
1ZIACP010170-11
Application #
8349577
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
11
Fiscal Year
2011
Total Cost
$1,371,718
Indirect Cost
Name
Division of Cancer Epidemiology and Genetics
Department
Type
DUNS #
City
State
Country
Zip Code
Kleinstern, Geffen; Camp, Nicola J; Goldin, Lynn R et al. (2018) Association of polygenic risk score with the risk of chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis. Blood 131:2541-2551
Bernatsky, Sasha; Velásquez García, Héctor A; Spinelli, John J et al. (2017) Lupus-related single nucleotide polymorphisms and risk of diffuse large B-cell lymphoma. Lupus Sci Med 4:e000187
Deziel, Nicole C; Nuckols, John R; Jones, Rena R et al. (2017) Comparison of industrial emissions and carpet dust concentrations of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in a multi-center U.S. study. Sci Total Environ 580:1276-1286
Teras, Lauren R; DeSantis, Carol E; Cerhan, James R et al. (2016) 2016 US lymphoid malignancy statistics by World Health Organization subtypes. CA Cancer J Clin :
Linet, Martha S; Brown, Linda M; Mbulaiteye, Sam M et al. (2016) International long-term trends and recent patterns in the incidence of leukemias and lymphomas among children and adolescents ages 0-19 years. Int J Cancer 138:1862-74
Nordsborg, Rikke Baastrup; Sloan, Chantel D; Shahid, Haseeb et al. (2015) Investigation of spatio-temporal cancer clusters using residential histories in a case-control study of non-Hodgkin lymphoma in the United States. Environ Health 14:48
Paltiel, Ora; Tikellis, Gabriella; Linet, Martha et al. (2015) Birthweight and Childhood Cancer: Preliminary Findings from the International Childhood Cancer Cohort Consortium (I4C). Paediatr Perinat Epidemiol 29:335-45
Czarnota, Jenna; Gennings, Chris; Colt, Joanne S et al. (2015) Analysis of Environmental Chemical Mixtures and Non-Hodgkin Lymphoma Risk in the NCI-SEER NHL Study. Environ Health Perspect 123:965-70
DellaValle, Curt T; Purdue, Mark P; Ward, Mary H et al. (2015) Validity of expert assigned retrospective estimates of occupational polychlorinated biphenyl exposure. Ann Occup Hyg 59:609-15
Stenehjem, J S; Kjærheim, K; Bråtveit, M et al. (2015) Benzene exposure and risk of lymphohaematopoietic cancers in 25?000 offshore oil industry workers. Br J Cancer 112:1603-12

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