With this award from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at Berea College will acquire a liquid chromatograph ion trap tandem mass spectrometer (LC/MS). This equipment will enhance research in a number of areas including a) the analysis of synthetic peptides and amino acids; b) the characterization of ginsenosides, active compounds found in ginseng that are potential cancer-fighting agents; c) analysis of polyphosphate samples; and d) the oxidation of high molecular weight alcohols by halogen complexes.
Liquid chromatography with mass spectrometric detection (LC/MS) is an extremely powerful technique used for the separation and analysis of complex mixtures. This instrument will substantially strengthen scientific research at Berea College, a primarily undergraduate institution. These studies will have a solid impact in the area of biochemistry, medicinal chemistry and synthetic chemistry.