Abstract

This NIEHS Center's Administrative Core is structured to provide both leadership and oversightto facilitate optimal management of Center and its Cores and Core Components. Each of the Cores and theircomponents are supervised by professional staff who are experts in their appointed areas of responsibility:Both physician scientists and PhD's work together to provide this leadership to advance the research andeducational programs of this Center. Both External and Internal Advisory Committees oversee this program ona regular basis.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES003828-23
Application #
7645971
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
2008-04-01
Project End
2009-03-31
Budget Start
2008-04-01
Budget End
2009-03-31
Support Year
23
Fiscal Year
2008
Total Cost
$198,210
Indirect Cost

  Institution

Name
Mount Desert Island Biological Lab
Department
Type
DUNS #
077470003
City
Salsbury Cove
State
ME
Country
United States
Zip Code
04672

  Publications

Hahn, Mark E; Karchner, Sibel I; Merson, Rebeka R (2017) Diversity as Opportunity: Insights from 600 Million Years of AHR Evolution. Curr Opin Toxicol 2:58-71
Telles, Connor J; Decker, Sarah E; Motley, William W et al. (2016) Functional and molecular identification of a TASK-1 potassium channel regulating chloride secretion through CFTR channels in the shark rectal gland: implications for cystic fibrosis. Am J Physiol Cell Physiol 311:C884-C894
Forrest Jr, John N (2016) THE SHARK RECTAL GLAND MODEL: A CHAMPION OF RECEPTOR MEDIATED CHLORIDE SECRETION THROUGH CFTR. Trans Am Clin Climatol Assoc 127:162-175
Schwarz, Julia S; de Jonge, Hugo R; Forrest Jr, John N (2015) Value of Organoids from Comparative Epithelia Models. Yale J Biol Med 88:367-74
Stahl, Klaus; Stahl, Maximilian; de Jonge, Hugo R et al. (2015) ANP and CNP activate CFTR expressed in Xenopus laevis oocytes by direct activation of PKA. J Recept Signal Transduct Res 35:493-504
Kelley, Catherine A; Decker, Sarah E; Silva, Patricio et al. (2014) Gastric inhibitory peptide, serotonin, and glucagon are unexpected chloride secretagogues in the rectal gland of the skate (Leucoraja erinacea). Am J Physiol Regul Integr Comp Physiol 306:R674-80
De Jonge, Hugo R; Tilly, Ben C; Hogema, Boris M et al. (2014) cGMP inhibition of type 3 phosphodiesterase is the major mechanism by which C-type natriuretic peptide activates CFTR in the shark rectal gland. Am J Physiol Cell Physiol 306:C343-53
Christian, Whitney V; Li, Na; Hinkle, Patricia M et al. (2012) ?-Subunit of the Ost?-Ost? organic solute transporter is required not only for heterodimerization and trafficking but also for function. J Biol Chem 287:21233-43
Barnes, D W (2012) Cell and molecular biology of the spiny dogfish Squalus acanthias and little skate Leucoraja erinacea: insights from in vitro cultured cells. J Fish Biol 80:2089-111
Miller, Hilary D; Clark, Bryan W; Hinton, David E et al. (2012) Anchoring ethinylestradiol induced gene expression changes with testicular morphology and reproductive function in the medaka. PLoS One 7:e52479

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