The broad goals of the ADRC at Columbia University include creating an infrastructure for research on AD and related disorders, fostering interdisciplinary collaborations across many departments, providing a rich training environment, and supporting outreach and patient recruitment. More globally, the goals of our ADRC extend to include participation in all national coordinating efforts, working with the national network of AD centers, and working with the National Institute on Aging and other organizations in their advocacy efforts. Embedded within these broad goals, in this reapplication a concentration will be placed on better defining normal aging and the transition from normal aging to the earliest stages of AD. The Administrative Core will act as the executive governing body of the ADRC that, with the guidance of its various committees, will provide the vision and leadership necessary to achieve the ADRC s goals. The Administrative Core will implement this vision by exercising managerial oversight over all aspects of the ADRC, which includes assuring the highest standards of scientific and bioethical conduct and assuring a judicious use of resources and funds. Dr. Scott Small will lead the core together with Dr. Richard Mayeux (co-director of the ADRC), Drs. Lawrence Honig and Yaakov Stern (deputy directors of the ADRC), Ms. Rosann Costa (Administrator of the ADRC), and Mr. Kevin Ramratan (Financial coordinator of the ADRC). Together and through continuous meetings they will achieve the ADRC s goals via a number of specific aims. These include: 1) Organize and direct monthly meetings with an executive committee made up of all core and project leaders. 2) Work closely with an external and internal advisory committee revamped to better fit the updated goals of the ADRC. 3) Work closely with the other cores to assure timely delivery of high quality clinical, genetic, and neuroimaging data, as well as biospecimens, to national consortia. 4) Work closely with a newly assembled resource committee . 5) Work closely with a newly assembled pilot project committee . 6) Assure and enhance the ADRC s outreach, advocacy, education, and training mission.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
5P50AG008702-27
Application #
9088232
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
Budget Start
2016-06-01
Budget End
2017-05-31
Support Year
27
Fiscal Year
2016
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Type
DUNS #
621889815
City
New York
State
NY
Country
United States
Zip Code
10032
Gallagher, Damien; Kiss, Alex; Lanctot, Krista et al. (2018) Depression and Risk of Alzheimer Dementia: A Longitudinal Analysis to Determine Predictors of Increased Risk among Older Adults with Depression. Am J Geriatr Psychiatry 26:819-827
Haaksma, Miriam L; Calderón-Larrañaga, Amaia; Olde Rikkert, Marcel G M et al. (2018) Cognitive and functional progression in Alzheimer disease: A prediction model of latent classes. Int J Geriatr Psychiatry 33:1057-1064
Bravo, Francisca Vaz; Da Silva, Jorge; Chan, Robin Barry et al. (2018) Phospholipase D functional ablation has a protective effect in an Alzheimer's disease Caenorhabditis elegans model. Sci Rep 8:3540
Ramsey, Christine M; Gnjidic, Danijela; Agogo, George O et al. (2018) Longitudinal patterns of potentially inappropriate medication use following incident dementia diagnosis. Alzheimers Dement (N Y) 4:1-10
Grivel, Margaux M; Leong, Wei; Masucci, Michael D et al. (2018) Impact of lifetime traumatic experiences on suicidality and likelihood of conversion in a cohort of individuals at clinical high-risk for psychosis. Schizophr Res 195:549-553
Hadjichrysanthou, Christoforos; McRae-McKee, Kevin; Evans, Stephanie et al. (2018) Potential Factors Associated with Cognitive Improvement of Individuals Diagnosed with Mild Cognitive Impairment or Dementia in Longitudinal Studies. J Alzheimers Dis 66:587-600
Hanfelt, John J; Peng, Limin; Goldstein, Felicia C et al. (2018) Latent classes of mild cognitive impairment are associated with clinical outcomes and neuropathology: Analysis of data from the National Alzheimer's Coordinating Center. Neurobiol Dis 117:62-71
Zhou, Zilu; Wang, Weixin; Wang, Li-San et al. (2018) Integrative DNA copy number detection and genotyping from sequencing and array-based platforms. Bioinformatics 34:2349-2355
Burke, Shanna L; Hu, Tianyan; Fava, Nicole M et al. (2018) Sex differences in the development of mild cognitive impairment and probable Alzheimer's disease as predicted by hippocampal volume or white matter hyperintensities. J Women Aging :1-25
Wang, Qi; Guo, Lei; Thompson, Paul M et al. (2018) The Added Value of Diffusion-Weighted MRI-Derived Structural Connectome in Evaluating Mild Cognitive Impairment: A Multi-Cohort Validation1. J Alzheimers Dis 64:149-169

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