Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM032110-14
Application #
2176440
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Project Start
1982-12-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Oregon State University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
053599908
City
Corvallis
State
OR
Country
United States
Zip Code
97339
Grochowski, Laura L; Zabriskie, T Mark (2006) Characterization of BlsM, a nucleotide hydrolase involved in cytosine production for the biosynthesis of blasticidin S. Chembiochem 7:957-64
Cone, Martha C; Yin, Xihou; Grochowski, Laura L et al. (2003) The blasticidin S biosynthesis gene cluster from Streptomyces griseochromogenes: sequence analysis, organization, and initial characterization. Chembiochem 4:821-8
Yin, Xihou; O'Hare, Thomas; Gould, Steven J et al. (2003) Identification and cloning of genes encoding viomycin biosynthesis from Streptomyces vinaceus and evidence for involvement of a rare oxygenase. Gene 312:215-24
Jackson, Michael D; Gould, Steven J; Zabriskie, T Mark (2002) Studies on the formation and incorporation of streptolidine in the biosynthesis of the peptidyl nucleoside antibiotic streptothricin F. J Org Chem 67:2934-41
Cone, M C; Petrich, A K; Gould, S J et al. (1998) Cloning and heterologous expression of blasticidin S biosynthetic genes from Streptomyces griseochromogenes. J Antibiot (Tokyo) 51:570-8
Zhang, Q; Gould, S J; Zabriskie, T M (1998) A new cytosine glycoside from Streptomyces griseochromogenes produced by the use in vivo of enzyme inhibitors. J Nat Prod 61:648-51
Gould, S J; Zhang, Q (1995) Cytosinine: pyridoxal phosphate tautomerase, a new enzyme in the blasticidin S biosynthetic pathway. J Antibiot (Tokyo) 48:652-6
Gould, S J; Guo, J (1994) Cytosylglucuronic acid synthase (cytosine: UDP-glucuronosyltransferase) from Streptomyces griseochromogenes, the first prokaryotic UDP-glucuronosyltransferase. J Bacteriol 176:1282-6
Nowak-Thompson, B; Gould, S J (1994) A simple assay for fluorescent siderophores produced by Pseudomonas species and an efficient isolation of pseudobactin. Biometals 7:20-4