Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM051377-08
Application #
6386064
Study Section
Molecular Biology Study Section (MBY)
Program Officer
Anderson, James J
Project Start
1994-08-01
Project End
2003-07-31
Budget Start
2001-08-01
Budget End
2002-07-31
Support Year
8
Fiscal Year
2001
Total Cost
$279,908
Indirect Cost
Name
University of California San Francisco
Department
Biochemistry
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Hao, Nan; O'Shea, Erin K (2011) Signal-dependent dynamics of transcription factor translocation controls gene expression. Nat Struct Mol Biol 19:31-9
Zhou, Xu; O'Shea, Erin K (2011) Integrated approaches reveal determinants of genome-wide binding and function of the transcription factor Pho4. Mol Cell 42:826-36
Kim, Harold D; Shay, Tal; O'Shea, Erin K et al. (2009) Transcriptional regulatory circuits: predicting numbers from alphabets. Science 325:429-32
Lam, Felix H; Steger, David J; O'Shea, Erin K (2008) Chromatin decouples promoter threshold from dynamic range. Nature 453:246-50
Lee, Young-Sam; Huang, Kexin; Quiocho, Florante A et al. (2008) Molecular basis of cyclin-CDK-CKI regulation by reversible binding of an inositol pyrophosphate. Nat Chem Biol 4:25-32
Kim, Harold D; O'Shea, Erin K (2008) A quantitative model of transcription factor-activated gene expression. Nat Struct Mol Biol 15:1192-8
Huang, Kexin; Ferrin-O'Connell, Ian; Zhang, Wei et al. (2007) Structure of the Pho85-Pho80 CDK-cyclin complex of the phosphate-responsive signal transduction pathway. Mol Cell 28:614-23
Lee, Young-Sam; Mulugu, Sashidhar; York, John D et al. (2007) Regulation of a cyclin-CDK-CDK inhibitor complex by inositol pyrophosphates. Science 316:109-12
Wykoff, Dennis D; Rizvi, Abbas H; Raser, Jonathan M et al. (2007) Positive feedback regulates switching of phosphate transporters in S. cerevisiae. Mol Cell 27:1005-13
Raser, Jonathan M; O'Shea, Erin K (2005) Noise in gene expression: origins, consequences, and control. Science 309:2010-3

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