Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD017864-11
Application #
2197545
Study Section
Reproductive Biology Study Section (REB)
Project Start
1983-09-01
Project End
1997-08-31
Budget Start
1995-09-01
Budget End
1997-08-31
Support Year
11
Fiscal Year
1995
Total Cost
Indirect Cost
Name
West Virginia University
Department
Physiology
Type
Schools of Dentistry
DUNS #
191510239
City
Morgantown
State
WV
Country
United States
Zip Code
26506
Nestor, Casey C; Bedenbaugh, Michelle N; Hileman, Stanley M et al. (2018) Regulation of GnRH pulsatility in ewes. Reproduction 156:R83-R99
Weems, Peyton; Smith, Jeremy; Clarke, Iain J et al. (2017) Effects of Season and Estradiol on KNDy Neuron Peptides, Colocalization With D2 Dopamine Receptors, and Dopaminergic Inputs in the Ewe. Endocrinology 158:831-841
Grachev, P; Porter, K L; Coolen, L M et al. (2016) Surge-Like Luteinising Hormone Secretion Induced by Retrochiasmatic Area NK3R Activation is Mediated Primarily by Arcuate Kisspeptin Neurones in the Ewe. J Neuroendocrinol 28:
Fergani, Chrysanthi; Mazzella, Leanne; Coolen, Lique M et al. (2016) Do Substance P and Neurokinin A Play Important Roles in the Control of LH Secretion in Ewes? Endocrinology 157:4829-4841
Weems, Peyton W; Goodman, Robert L; Lehman, Michael N (2015) Neural mechanisms controlling seasonal reproduction: principles derived from the sheep model and its comparison with hamsters. Front Neuroendocrinol 37:43-51
Goodman, Robert L; Coolen, Lique M; Lehman, Michael N (2014) A role for neurokinin B in pulsatile GnRH secretion in the ewe. Neuroendocrinology 99:18-32
Porter, K L; Hileman, S M; Hardy, S L et al. (2014) Neurokinin-3 receptor activation in the retrochiasmatic area is essential for the full pre-ovulatory luteinising hormone surge in ewes. J Neuroendocrinol 26:776-84
Goodman, Robert L; Hileman, Stanley M; Nestor, Casey C et al. (2013) Kisspeptin, neurokinin B, and dynorphin act in the arcuate nucleus to control activity of the GnRH pulse generator in ewes. Endocrinology 154:4259-69
Nestor, Casey C; Coolen, Lique M; Nesselrod, Gail L et al. (2013) Evidence that orphanin FQ mediates progesterone negative feedback in the ewe. Endocrinology 154:4249-58
Merkley, Christina M; Porter, Katrina L; Coolen, Lique M et al. (2012) KNDy (kisspeptin/neurokinin B/dynorphin) neurons are activated during both pulsatile and surge secretion of LH in the ewe. Endocrinology 153:5406-14

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