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Effectiveness and cost-effectiveness of coaching models to promote implementationChild neglect is the dominant problem in the child welfare system, accounting for over 64% of cases annually. Neglect is also the most serious form of maltreatment, leading to an...
Dissecting the role for IL-15 in CD8+ T cell homeostasis in human lupusSystemic lupus erythematosus (SLE) is an autoimmune-mediated inflammatory disease of unknown etiology. The pathologic hallmarks of SLE are altered immune responses to autoantigens with autoantibody production and subsequent tissue injury,...
Shortage of Health Professionals in Rural AreasAn ongoing challenge to the provision of state of the science, empirically tested mental health interventions in rural areas is a shortage of mental health and general health care professionals....
Body Weight Supported Ambulation Training After SciFundamental strategies first adopted in major centers 20 years ago for the physical rehabilitation of persons with sub-acute or chronic spinal cord injury (SCI) have changed little since that time....
Coupled Emission Microscopy for the BiosciencesFluorescence imaging is used widely in almost all the biosciences. Examples include imaging of microscope slides with spots of DNA or proteins, multiplexed assays of classes of molecules like cytokines...
Scaling of transcript abundance with cell size and the commitment to cell divisionAll cells must grow to a minimum size?the ?critical size??before they can commit to cell division. This size requirement prevents cells from becoming too big or too small, and it...
Lipid signaling in Hippo pathway regulationOverthepastdecades,theHippopathwayhasbeenrecognizedasacrucialsignalingpathwaythat controlsorganandtissuesize,byrestrictingcellproliferationandanti-apoptosis.TheHippopathwaycanbe regulatedbyawiderangeofextracellularsignaling,includingperceivedphysical...
Project 4: Mathematical Modeling Studies of Anesthetic ActionPROJECT 4: MODELING STUDIES OF ANESTHETIC ACTION General anesthesia is a fascinating man-made, neurophysiological phenomenon that has been developed empirically over many years to enable safe and humane performance of...
The postdoctoral training period is nearly essential for all research scientists who aspire to lead a research laboratory in a university or non-profit research center. To characterize the transition of scientists from postdoc to established PI, we previously conducted an analysis of how many postdocs with a NIH-sponsored F32 fellowship went on to become PIs of a R-esearch grant. In 2006, NIH int...
Previously, we calculated the fraction of the R01 grant pool that each institution has obtained in 2013, and how this fraction has changed over time. We now wanted to perform a complementary analysis, determining institutional variability in the length of time that individual PIs are able to maintain NIH grant funding. This analysis would be of interest to university administrators who want to rec...
In our database, for any grant we report "Related Projects" that are renewals of ongoing projects from individual investigators. We wanted to improve this by identifying "Related Projects" more generally in which we group different grants based on the text in the abstract. We analyzed the similarities of 2013 NIH grant abstracts with lengths of at least 100 words (disregarding the public health r...
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