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RF-penetrable PET ring for acquiring simultaneous time-of-flight PET and MRI dataWe propose to create and explore a radio-frequency (RF)-penetrable positron emission tomography (PET) system technology that can be inserted into a magnetic resonance imaging (MRI) system for acquiring simultaneous PET/MRI...
Vasoprotective Actions of Autologous Cell TransferThe objective of this proposal is to characterize and enhance the vasoprotective effects of culture-modified mononuclear cells (CMMCs) and endothelial outgrowth cells (EOCs) in an animal model of acute vascular...
Perceptual Experience and Spoken Word RecognitionThe goal of the proposed research is to discover how perceptual experience affects the spoken word recognition processing system. This research capitalizes on wide individual differences in linguistic experience among...
Structure and Function of Myc Family GenesThe N-myc gene is frequently amplified and overexpressed in a highly restricted set of related human tumors, including neuroblastomas and retinoblastomas. We have demonstrated that the N-myc gene encodes a...
Impact of Aspirin on the Gut Microbiome and Mucosal MicroenvironmentSubstantial evidence supports health benefits associated with aspirin use, particularly for individuals at increased risk for cardiovascular disease (CVD) and colorectal cancer (CRC). In 2016, the U.S. Preventive Services Task...
Mentored Education for Dissemination and Implementation Science (MEDIS) ProgramChronic diseases are the leading causes of death and disability in the United States, and have the capacity to bankrupt the American healthcare system as drivers of the nation's $3.3...
Regulation of X-chromosome Inactivation and Imprinting by Non-coding ElementsStudies from the last several years have repeatedly highlighted the importance of long noncoding RNAs (lncRNA) in epigenetic regulation, development, and disease. However, the mechanisms by which RNAs control these...
The University of Arkansas for Medical Sciences Initiative for Maximizing Student Development ProgramThe low number of college graduates from underrepresented (UR) groups in Arkansas, together with the small number of UR students nationally who graduate in the biological sciences, results in a...
The postdoctoral training period is nearly essential for all research scientists who aspire to lead a research laboratory in a university or non-profit research center. To characterize the transition of scientists from postdoc to established PI, we previously conducted an analysis of how many postdocs with a NIH-sponsored F32 fellowship went on to become PIs of a R-esearch grant. In 2006, NIH int...
Previously, we calculated the fraction of the R01 grant pool that each institution has obtained in 2013, and how this fraction has changed over time. We now wanted to perform a complementary analysis, determining institutional variability in the length of time that individual PIs are able to maintain NIH grant funding. This analysis would be of interest to university administrators who want to rec...
In our database, for any grant we report "Related Projects" that are renewals of ongoing projects from individual investigators. We wanted to improve this by identifying "Related Projects" more generally in which we group different grants based on the text in the abstract. We analyzed the similarities of 2013 NIH grant abstracts with lengths of at least 100 words (disregarding the public health r...
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