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Dissociating mTBI and PTSD brain activity at restThe goal of the proposed project is to determine whether large-scale neural networks are differentially affected in mild traumatic brain injury (mTBI) and posttraumatic stress disorders (PTSD), two commonly co-occurring...
Adaptation of New Statistical Ideas for MedicineUseful statistical ideas are drawn into biomedical practice from a wide range of sources, including theoretical research and developments in other application areas. The long-term purpose of this grant is...
Cell Surface Interactions in Neural Crest Development Cellular Immunity to HIV in Mothers and Infants Developmental FundsCCSG Developmental Funds are critical to the success of Dana-Farber/Harvard Cancer Center. The Center carefully invests these funds to stimulate investigation, member engagement, and inter-programmatic collaboration in high priority areas....
Novel Enediyne-Based Antibody-Drug Conjugates for CancersBoth the two FDA-approved antibody-drug conjugates (ADCs) (Adcetris and Kadcyla) and nearly all ADCs in clinical trials are prepared by randomly conjugating drugs to lysine or cysteine residues in the...
Core 01: Cancer PharmacologyThe Cancer Pharmacology Core provides the necessary expertise and resources to design and undertake pharmacokinetic (PK) studies in Phase I and II clinical trials, and preclinical investigations. Services include the...
Optimizing Tobacco Treatment for Smokers Seeking Lung Cancer ScreeningThere is a timely and urgent need to understand and leverage the context of lung cancer screening to deliver smoking cessation treatment and promote cessation among individuals at high risk...
The postdoctoral training period is nearly essential for all research scientists who aspire to lead a research laboratory in a university or non-profit research center. To characterize the transition of scientists from postdoc to established PI, we previously conducted an analysis of how many postdocs with a NIH-sponsored F32 fellowship went on to become PIs of a R-esearch grant. In 2006, NIH int...
Previously, we calculated the fraction of the R01 grant pool that each institution has obtained in 2013, and how this fraction has changed over time. We now wanted to perform a complementary analysis, determining institutional variability in the length of time that individual PIs are able to maintain NIH grant funding. This analysis would be of interest to university administrators who want to rec...
In our database, for any grant we report "Related Projects" that are renewals of ongoing projects from individual investigators. We wanted to improve this by identifying "Related Projects" more generally in which we group different grants based on the text in the abstract. We analyzed the similarities of 2013 NIH grant abstracts with lengths of at least 100 words (disregarding the public health r...
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