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The entirety of funding information.
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Kentucky BIRCWH Program: Training the Next Generation of Women's Health ScholarsThe University of Kentucky (UK) is uniquely positioned to continue using exceptional and outstanding research infrastructure to train the next generation of women's health scholars. We choose to focus our...
Biphasic mechanisms of injury and repair in stroke therapyBiphasic mechanisms of injury and repair in stroke therapy: The role of oxidative stress in stroke is well accepted. However, the recent SAINT-2 clinical trial of a free radical spin...
Evolution of Genome IncompatibilitiesIncompatibilities between genomes are the source of reproductive isolation between species. Although genome incompatibilities are a central feature of the evolutionary process in sexual organisms, little is known about how...
Fimbriae of S Sanguis - Gnetic AnalysisThis proposal concerns the isolation of adhesion-fimbrial (fim+) genes from Streptococcus sanguis and the expression of these genes in E. coli. The fimbrial proteins produced in E. coli will be...
Research CoreThe ability to generate, store and analyze high throughput genomic data is critical for many aspects of modern biology, and especially for human genetics. The Clemson University Genomics and Bioinformatics...
Forward Genetic Analysis of Human Nuclear Long Non-Coding RNAsCertain human nuclear long non-coding RNAs (lncRNAs) represent well-established promising targets for the treatment of cancer, developmental and viral diseases; manipulating their levels is expected to provide therapeutic interventions for...
Research Project 2Congenital disorders of glycosylation (CDGs) are a heterogeneous group of rare inherited diseases caused by mutations in genes involved in protein glycosylation. The most common CDG, PMM2-CDG, results from mutations...
Research Project 3Transposable elements (TEs, also referred to as jumping genes or mobile elements) are extraordinary contributors to eukaryotic genome diversity, including in humans. TEs make up more than 50% of the...
The postdoctoral training period is nearly essential for all research scientists who aspire to lead a research laboratory in a university or non-profit research center. To characterize the transition of scientists from postdoc to established PI, we previously conducted an analysis of how many postdocs with a NIH-sponsored F32 fellowship went on to become PIs of a R-esearch grant. In 2006, NIH int...
Previously, we calculated the fraction of the R01 grant pool that each institution has obtained in 2013, and how this fraction has changed over time. We now wanted to perform a complementary analysis, determining institutional variability in the length of time that individual PIs are able to maintain NIH grant funding. This analysis would be of interest to university administrators who want to rec...
In our database, for any grant we report "Related Projects" that are renewals of ongoing projects from individual investigators. We wanted to improve this by identifying "Related Projects" more generally in which we group different grants based on the text in the abstract. We analyzed the similarities of 2013 NIH grant abstracts with lengths of at least 100 words (disregarding the public health r...
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