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The entirety of funding information.
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Asthma Care Quality in Varying Managed Medicaid PlansBackground. Poor children with asthma have heightened vulnerability to adverse outcomes. Increasing numbers of children covered by Medicaid are being served by managed care organizations (MCOs), whose quality of care...
Function and Developmental Regulation of Matrix ReceptorsIntegrins and other cell surface receptors for extracellular matrix proteins such as fibronectin and vitronectin play roles in embryonic development and wound healing. Our studies suggest important roles for integrins...
Spectral asymptotics for stable processesThe proposed projects will investigate several mathematical problems which lie at the interface of probability, partial differential equations and spectral theory. On the probability side, the problems are formulated in...
Permeability Enhancement by Fluid Pressure OscillationsThis project will investigate fluid flow within rock masses in the shallow regions of Earth's crust, from the surface to ~10 km. Our work will focus on how dynamic stresses,...
Modulation of Protein Biogenesis and Secretion by Natural Product Translocon LigandsLoss of homeostasis in the cellular secretory pathway is implicated in major human diseases such as cancer, diabetes and inflammation. Secreted and cell-wall proteins are also critical for host infection...
Molecular and cellular mechanisms regulating actin dynamicsThe overall goal of the NIGMS-funded research in my lab is to define the molecular and cellular mechanisms underlying dynamic rearrangements of the actin cytoskeleton, and to explore how these...
Inflammatory mechanisms responsible for the development of multiple organ dysfunction in pediatric patients following allogeneic blood and marrow transplantation (BMT).Allogeneic blood and marrow transplantation (allo-BMT) is the only curative therapy for many pediatric patients with malignant and non-malignant disorders. Unfortunately, treatment-related complications remain a major barrier to successful outcomes....
Fluorescence tools that illuminate biology and inspire translationUnderstanding the mechanisms of protein and organelle function and dysfunction in disease requires a detailed and dynamic analysis of molecular structures and interactions in live cells. The long-term goal of...
The postdoctoral training period is nearly essential for all research scientists who aspire to lead a research laboratory in a university or non-profit research center. To characterize the transition of scientists from postdoc to established PI, we previously conducted an analysis of how many postdocs with a NIH-sponsored F32 fellowship went on to become PIs of a R-esearch grant. In 2006, NIH int...
Previously, we calculated the fraction of the R01 grant pool that each institution has obtained in 2013, and how this fraction has changed over time. We now wanted to perform a complementary analysis, determining institutional variability in the length of time that individual PIs are able to maintain NIH grant funding. This analysis would be of interest to university administrators who want to rec...
In our database, for any grant we report "Related Projects" that are renewals of ongoing projects from individual investigators. We wanted to improve this by identifying "Related Projects" more generally in which we group different grants based on the text in the abstract. We analyzed the similarities of 2013 NIH grant abstracts with lengths of at least 100 words (disregarding the public health r...
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