SUNY Downstate Medical Center (SUNY-DMC) proposes to renew its current AITRP by continuing to focus on the rapidly expanding injection drug use mediated HIV epidemic in Eastern Europe and Central Asia. The NYS International Training and Research Program (NYS-ITRP) was initiated as a Fogarty funded AIDS International Training and Research Program (AITRP) in 1993 to focus on Central Europe. It has since expanded to include 3 Baltic States: Armenia, Georgia, and Russia. This program represents a unique merging of an academic medical center, a school of public health and a state department of health, which combined with other training assets in New York State, allows us to respond to the continuing challenges of preventing new infections in the region. During the past 16 years, the combined AITRP has provided support for 76 long-term trainees, 3 of whom are still in training. They have been remarkably productive publishing over 650 articles and providing strong academic and public health leadership regionally and internationally. With this application we propose to expand our activities to Kazakhstan and Ukraine two countries with large IDU driven epidemics where we have identified strong local partners. We will continue to provide ongoing training to Russia, Georgia and Estonia and expand our training programs to include nurse training as well as enhance the development of regional public health training. The program's aims are: a. To build human resources capacity in our collaborating countries by providing long-term training in the US and ultimately in-country in population-based, biomedical and implementation research; b. To foster collaborative, interdisciplinary in-country research networks among our trainees and those supported by other programs; c. To utilize academic resources in New York State as well as the Fogarty network to ensure that the most productive assets are utilized for training efforts; d. To build in-country research capacity and productivity via a continuous mentoring process; e. To assist in the transition of in-country assets Into regional centers of excellence. In meeting its aims the NYS-ITRP's overall goal is to train a new generation of investigators capable of working in multidisciplinary environments capable of producing the research necessary to guide national priorities for successful treatment, prevention and care.

Public Health Relevance

HIV rates are rising rapidly in Eastern Europe and Central Asia primarily driven by injection drug use. A number of social, economic and historical factors place this region at high risk for a continued increase in new infections in both drug users and their sexual partners. The training supported by this proposal will assist in developing critically needed control measures in the region.

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
International Research Training Grants (D43)
Project #
2D43TW000233-16
Application #
7917827
Study Section
Special Emphasis Panel (ZRG1-ICP2-B (52))
Program Officer
Mcdermott, Jeanne
Project Start
1993-06-01
Project End
2015-04-30
Budget Start
2010-06-01
Budget End
2011-04-30
Support Year
16
Fiscal Year
2010
Total Cost
$747,046
Indirect Cost
Name
Suny Downstate Medical Center
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
040796328
City
Brooklyn
State
NY
Country
United States
Zip Code
11203
Makarenko, Iuliia; Mazhnaya, Alyona; Marcus, Ruthanne et al. (2018) Concurrent drug injection during opioid agonist treatment among people who inject drugs in Ukraine. J Subst Abuse Treat 87:1-8
Iakunchykova, Olena; Meteliuk, Anna; Zelenev, Alexei et al. (2018) Hepatitis C virus status awareness and test results confirmation among people who inject drugs in Ukraine. Int J Drug Policy 57:11-17
Zelenev, Alexei; Li, Jianghong; Mazhnaya, Alyona et al. (2018) Hepatitis C virus treatment as prevention in an extended network of people who inject drugs in the USA: a modelling study. Lancet Infect Dis 18:215-224
Mazhnaya, Alyona; Meteliuk, Anna; Barnard, Tetiana et al. (2017) Implementing and scaling up HCV treatment services for people who inject drugs and other high risk groups in Ukraine: An evaluation of programmatic and treatment outcomes. Int J Drug Policy 47:187-195
Czerwinski, Michal; Grabarczyk, Piotr; Stepien, Malgorzata et al. (2017) What weighs more-low compliance with self-deferral or minor medical procedures? Explaining the high rate of hepatitis C virus window-period donations in Poland. Transfusion 57:1998-2006
Makarenko, Iuliia; Ompad, D C; Sazonova, Y et al. (2017) Trends in Injection Risk Behaviors among People Who Inject Drugs and the Impact of Harm Reduction Programs in Ukraine, 2007-2013. J Urban Health 94:104-114
Ompad, Danielle C; Wang, Jiayu; Dumchev, Konstantin et al. (2017) Patterns of harm reduction service utilization and HIV incidence among people who inject drugs in Ukraine: A two-part latent profile analysis. Int J Drug Policy 43:7-15
Makarenko, Iuliia; Mazhnaya, Alyona; Marcus, Ruthanne et al. (2017) Willingness to pay for opioid agonist treatment among opioid dependent people who inject drugs in Ukraine. Int J Drug Policy 45:56-63
Iakunchykova, Olena P; Burlaka, Viktor (2017) Correlates of HIV and Inconsistent Condom Use Among Female Sex Workers in Ukraine. AIDS Behav 21:2306-2315
Vasylyeva, Tetyana I; Friedman, Samuel R; Gensburg, Lenore et al. (2017) Engagement in sex work does not increase HIV risk for women who inject drugs in Ukraine. J Public Health (Oxf) 39:e103-e110

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