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The entirety of funding information.
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Dissecting the biochemical role of BOK in regulating cellular life and deathApoptosis, a form of programmed cell death, is a highly orchestrated mechanism for maintaining the critical balance between new and dying cells during development and throughout life. Disruption of this...
Centers for Public Health Preparedness Biological and Physiological Sciences Review Section Cassp - Preschool Focus in North Carolina (PQ5) Consequences of imbalanced mitophagy and mitochondrial biogenesis in cancerThe proposed research tests the novel concept that mitophagy and mitochondrial biogenesis are coordinately regulated to promote both turnover of old mitochondria but also to facilitate rapid and wholesale re-programming...
?-3 fatty acid-derived mediators promote resolution of inflammation: Uncovering new strategies for preventing colitis-associated colon cancerThe pathogenesis of chronic inflammatory bowel disease (IBD) is driven by dysregulation of both intestinal epithelial and immune cell functions. Chronic IBD places patients at increased risk for developing colitis-...
Project 1: Effect of Iron Deprivation on H. pylori-induced Gastric CarcinogenesisH. pylori is the strongest known risk factor for gastric cancer. One H. pylori determinant that augments cancer risk is the cag type IV secretion system (T4SS) which exports an...
Cutaneous T cell lymphoma: a paradigm for dissecting susceptibility and resistance to checkpoint inhibition therapyCutaneous T-cell lymphoma (CTCL) represents a blood cancer that originates in the skin. Unfortunately, this disfiguring malignancy continues to be incurable. The etiology of this disease remains to be elucidated....
The postdoctoral training period is nearly essential for all research scientists who aspire to lead a research laboratory in a university or non-profit research center. To characterize the transition of scientists from postdoc to established PI, we previously conducted an analysis of how many postdocs with a NIH-sponsored F32 fellowship went on to become PIs of a R-esearch grant. In 2006, NIH int...
Previously, we calculated the fraction of the R01 grant pool that each institution has obtained in 2013, and how this fraction has changed over time. We now wanted to perform a complementary analysis, determining institutional variability in the length of time that individual PIs are able to maintain NIH grant funding. This analysis would be of interest to university administrators who want to rec...
In our database, for any grant we report "Related Projects" that are renewals of ongoing projects from individual investigators. We wanted to improve this by identifying "Related Projects" more generally in which we group different grants based on the text in the abstract. We analyzed the similarities of 2013 NIH grant abstracts with lengths of at least 100 words (disregarding the public health r...
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