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anonymous on The Rise and Fall of the Dominant FewThe New York schools, like Mount Sinai, are some of the most cutthroat places to work. They have no problem with reducing your salary down to 10% if your grants...
BD on A study to improve the fit of HIV prevention methodsFinally the kind of research that I want my government to pay for! And it is already in the stage of clinical trials. :)
random observer on Seattle-Lausanne-Kampala CTUThis grant has reviewer comments in Abstract! How could it be funded at <10% success rate if 'Reviewers express a strong concern ...
PI on The Rich and the Rest Looking at the R01 distribution, the trend for 2014 & 2015 does not look that hot.
Joseph Hein on Hygromycin A: Activity, Biosynthesis, Export, Resistance and RegulationWe are desperate for this drug for stubborn Lyme cases.
Hadi Najafi Pazhooh on SBIR Phase I: Molecular Composites of Functional Silica Networks within Natural Rubber Compounds for Green TiresI am a graduated polymer engineering student from the Isfahan University of Technology in Iran and interested in doing research on polymer composites. It will be indeed an honor for...
Yennifer on Testerone TrialPara usar productos gratis
Michael Cleary principal on Physical exercise and Blood-brain communication: exosomes, Klotho and choroid plexusCongratulations and well done from Klotho International Academy You have advanced and confirmed the value of the exosomed release of the Klotho protein
A universal genome editing strategy to develop an airway stem cell therapy for cystic fibrosisCystic fibrosis (CF) is caused by mutations in a single gene called the cystic fibrosis transmembrane conductance regulator (CFTR), which codes for an ion channel that transports Cl- ions. CF...
Impact of Occult Hepatitis C Virus Infection in Progression of Liver DiseasesChronic Hepatitis C virus (HCV) infection is the leading cause of decompensated cirrhosis and hepatocellular carcinoma (HCC), which account for over 15,000 deaths annually in the US. The recent advancements...
Methylphenidate, Serotonin and Dopamine InteractionsThe clinical use of methylphenidate (MPH, Ritalin) for treatment of attention-deficit/hyperactivity disorder is widespread, and there is a growing problem of MPH abuse, especially in college-age adults. College students use...
Hand Movement Monitors for Computerized CommunicationGreenleaf Medical is a major supplier of computer based products for the evaluation of hand function. At Greenleaf Medical, the investigators have developed the Glove Talker system for people with...
Neuropathic vs. inflammatory pain in chronic pancreatitis: can unique biomarkers be identified to guide mechanistic approaches to pain treatment?Chronic pancreatitis (CP) is often accompanied by profoundly debilitating pain that is quite difficult to treat. There are no tools available in clinics to properly characterize the subtype of pain...
Forkhead Box A3 and Bile Acid MetabolismBile acids (BAs) are synthesized from cholesterol. BA synthesis is tightly controlled to prevent incidence of diseases, such as cholestasis, gallstone disease, malabsorption, hypercholesterolemia, etc. BAs are important for nutrient...
Modeling intestinal dysfunction in HIV infection with organoid technologyDisruption of intestinal epithelial barrier function is an important cause of HIV-associated chronic immune activation but underlying molecular mechanisms are not known. The central hypothesis of this proposal is that...
Molecular mechanisms to maintain ER redox balanceReactive oxygen species (ROS) are a significant byproduct of many intracellular and extracellular events. Cellular systems exist to limit ROS accumulation within cells; a loss of fidelity for these pathways...
The postdoctoral training period is nearly essential for all research scientists who aspire to lead a research laboratory in a university or non-profit research center. To characterize the transition of scientists from postdoc to established PI, we previously conducted an analysis of how many postdocs with a NIH-sponsored F32 fellowship went on to become PIs of a R-esearch grant. In 2006, NIH int...
Previously, we calculated the fraction of the R01 grant pool that each institution has obtained in 2013, and how this fraction has changed over time. We now wanted to perform a complementary analysis, determining institutional variability in the length of time that individual PIs are able to maintain NIH grant funding. This analysis would be of interest to university administrators who want to rec...
In our database, for any grant we report "Related Projects" that are renewals of ongoing projects from individual investigators. We wanted to improve this by identifying "Related Projects" more generally in which we group different grants based on the text in the abstract. We analyzed the similarities of 2013 NIH grant abstracts with lengths of at least 100 words (disregarding the public health r...
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