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The entirety of funding information.
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Protein quality control mechanisms of novel soluble substratesProtein quality control mechanisms are required for normal cellular health to prevent disease and avoid premature senescence. Unique mutant proteins are substrates of these pathways, are recognized by protein quality...
Structure and Synthesis of DNAKinetoplast DNA is the mitochondrial DNA of trypanosomes and related parasitic protozoa. It is an unusual DNA, consisting of DNA circles that are catenated into a giant network. The network...
Grants for Faculty Development in Family Medicine Immune Processes in the Pregnant and Nonpregnant UterusThe uterus is a unique mucosal organ because it must not only cope with the hazards of exposure to the external environment, but it must serve as the recipient site...
Functions of the reovirus capsidThe proposed research uses mammalian reovirus (MRV) to define how a single capsid protein, ?1, influences distinct functions of the viral capsid. MRV particles are comprised of two concentric protein...
Metabolic factors that control the spectrum of human tuberculosisThe absence of an effective vaccine for tuberculosis means that TB control relies on the early diagnosis and effective treatment of infectious cases, which is compromised by the relatively low...
Metabolic checkpoint in dendritic cell subsets and adaptive immunityDendritic cells (DCs) are the central regulators of T cell immunity and tolerance. Conventional type 1 or CD8?+ DCs (cDC1) are critical for anti-tumor immunity by presenting antigens to CD8...
Allergen T cell epitopes and phenotypes in peanut allergy and immunotherapyfor Overview The proposed Center will perform mechanistic studies of allergen-specific T cell responses in peanut allergic subjects through two synergistic projects. The first project will investigate the phenotypic and...
The postdoctoral training period is nearly essential for all research scientists who aspire to lead a research laboratory in a university or non-profit research center. To characterize the transition of scientists from postdoc to established PI, we previously conducted an analysis of how many postdocs with a NIH-sponsored F32 fellowship went on to become PIs of a R-esearch grant. In 2006, NIH int...
Previously, we calculated the fraction of the R01 grant pool that each institution has obtained in 2013, and how this fraction has changed over time. We now wanted to perform a complementary analysis, determining institutional variability in the length of time that individual PIs are able to maintain NIH grant funding. This analysis would be of interest to university administrators who want to rec...
In our database, for any grant we report "Related Projects" that are renewals of ongoing projects from individual investigators. We wanted to improve this by identifying "Related Projects" more generally in which we group different grants based on the text in the abstract. We analyzed the similarities of 2013 NIH grant abstracts with lengths of at least 100 words (disregarding the public health r...
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