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The entirety of funding information.
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Eukaryotic Chromatin Structure and Gene RegulationWe have continued studies of chromatin structure and the regulation of eukaryotic gene expression by analysis of ATP-dependent chromatin remodeling enzymes. We completed studies on the biology of ATP-dependent chromatin...
Functional and Molecular Dissection of Myeloproliferative Neoplasm Stem CellsThe candidate, Dr. Ann Mullally, presents a 5-year career development plan that seeks to investigate the functional and molecular properties of myeloproliferative neoplasm (MPN) hematopoietic stem cells (HSCs), using in...
Center for Vulnerable Populations ResearchThe mission of the Center for Vulnerable Populations Research (CVPR) is to enhance strengths of communities to eliminate health disparities faced by vulnerable populations (VPs), with a particular focus on...
Nutritional Taurine - Pregnancy and OutcomeResults from the first funding period have demonstrated conclusively that dietary taurine is essential for normal feline pregnancy and outcome, and that its absence from the diet results in excessive...
Regulatory Impact on Vape Shops and Young Adults' Use of ENDSElectronic nicotine delivery systems (ENDS) have emerged in the US market, with use and awareness rapidly increasing in recent years, particularly in young adults. While ENDS may facilitate harm reduction...
DNA-Protein Crosslinks and Genomic InstabilityDNA damage is the major cause of genomic instability, a hallmark of cancer. DNA-protein crosslinks (DPCs) are one of most toxic forms of DNA damage, interfering with the DNA replication...
Identifying Immune Mechanisms for Microbiota-Inhibition of Anti-PD-L1 Tumor ResponseImmune checkpoint blockade is a recent cancer therapeutic strategy that has enabled durable responses in 15- 40% of patients for several cancers by licensing CD8+ tumor infiltrating lymphocytes to kill...
Improved cancer screening with synthetic and stationary 3D mammographyMotivation and clinical relevance: Early detection is the key to surviving breast cancer. This project aims to complete the development of an experimental carbon nanotube-enabled x-ray imaging device for breast...
The postdoctoral training period is nearly essential for all research scientists who aspire to lead a research laboratory in a university or non-profit research center. To characterize the transition of scientists from postdoc to established PI, we previously conducted an analysis of how many postdocs with a NIH-sponsored F32 fellowship went on to become PIs of a R-esearch grant. In 2006, NIH int...
Previously, we calculated the fraction of the R01 grant pool that each institution has obtained in 2013, and how this fraction has changed over time. We now wanted to perform a complementary analysis, determining institutional variability in the length of time that individual PIs are able to maintain NIH grant funding. This analysis would be of interest to university administrators who want to rec...
In our database, for any grant we report "Related Projects" that are renewals of ongoing projects from individual investigators. We wanted to improve this by identifying "Related Projects" more generally in which we group different grants based on the text in the abstract. We analyzed the similarities of 2013 NIH grant abstracts with lengths of at least 100 words (disregarding the public health r...
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