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Statistical Analysis of Image FeaturesThe aim of this project is the development of statistical methods that either take into account interpixel correlation, or apply global image transform methods that permit an analysis of uncorrelated...
Regulation of Cellular Proliferation and Diversity in DrosophilaGenes involved in the determination and differentiation of segmental identity in Drosophila melanogaster have been identified by genetic interactions with the homeotic genes already known to be required. Many new...
The role of marine Crenarchaeota in nitrification and links among biogeochemical processes in the eastern tropical North Pacific and Gulf of CaliforniaNitrification, the two-step oxidation of ammonia to nitrate via nitrite, plays a critical role in the global nitrogen (N) cycle by changing the form in which N occurs, and consequently...
Acquisition of a High Temperature Micro-hardness Tester (Materials Research) Agonism of DR3 for Enhanced Treg Cell Function in IBDThe immune-mediated, chronic inflammation in inflammatory bowel disease (IBD) leads to flares that often require patients to be treated with life-long biologic therapy. Recently, efforts in IBD disease management have...
Microbial-derived factors regulating mucosal wound healingInflammatory bowel disease (IBD) currently afflicts more than 3.1 million people in the U.S. with over 100,000 new cases each year. Patients with IBD experience persistent and relapsing gastrointestinal tract...
In utero gene editing to cure a metabolic liver diseaseMetabolic liver diseases are the second most common indication for a pediatric liver transplant. Hereditary tyrosinemia type I (HT1) is a metabolic liver disease that results from FAH gene mutations...
Mechanisms associated with diet-induced colitisMany studies support a role for IL-23 in the pathogenesis of IBD, but it is unclear how IL-23 expression in vivo promotes colitis. To better study the biology of IL-23...
The postdoctoral training period is nearly essential for all research scientists who aspire to lead a research laboratory in a university or non-profit research center. To characterize the transition of scientists from postdoc to established PI, we previously conducted an analysis of how many postdocs with a NIH-sponsored F32 fellowship went on to become PIs of a R-esearch grant. In 2006, NIH int...
Previously, we calculated the fraction of the R01 grant pool that each institution has obtained in 2013, and how this fraction has changed over time. We now wanted to perform a complementary analysis, determining institutional variability in the length of time that individual PIs are able to maintain NIH grant funding. This analysis would be of interest to university administrators who want to rec...
In our database, for any grant we report "Related Projects" that are renewals of ongoing projects from individual investigators. We wanted to improve this by identifying "Related Projects" more generally in which we group different grants based on the text in the abstract. We analyzed the similarities of 2013 NIH grant abstracts with lengths of at least 100 words (disregarding the public health r...
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