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The entirety of funding information.
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Brown University Postbaccalaureate Research Education ProgramAssessment of current programs designed to increase diversity in STEM disciplines at Brown University has revealed the need to specifically address the critical transition from undergraduate into doctoral training programs....
Free Text Gene Name Recognition1) I have been a co-organizer of the BioCreative Workshops since 2005 and have taken part in BioCreative II (2007), BioCreative III (2010), and the BioCreative-2012 Workshop (2012). The overall...
Small molecule inhibitor of amyloid precursor protein synthesisThe product that will result from this SBIR is a small molecule drug therapy for Alzheimer's Disease (AD) that works by inhibiting amyloid precursor protein synthesis. AD accounts for two-thirds...
Antidepressant Treatment to Reduce HIV Risk Among IdusSubstance abusers with other psychiatric disorders pose complex therapeutic challenges. The importance of these associations is most telling among injection drug users (IDUs) in whom drug use conveys the risk...
Diabetes Progression with Metabolomic Profiling in Starr County Mexican AmericansType 2 diabetes spans a broad and complex phenotypic spectrum, but its metabolic changes and progression start early, even years prior to diagnosis. Interventions have considerable preventive promise in these...
The impact of dysbiosis and the IL-12/23 signaling axis on IBD-associated bone loss.Inflammatory bowel disease (IBD) is characterized by severe gastrointestinal inflammation and changes in the intestinal microbiota. Many IBD patients also experience extra-intestinal manifestations. Skeletal abnormalities are a frequent extra-intesti...
Agonism of DR3 for Enhanced Treg Cell Function in IBDThe immune-mediated, chronic inflammation in inflammatory bowel disease (IBD) leads to flares that often require patients to be treated with life-long biologic therapy. Recently, efforts in IBD disease management have...
Microbial-derived factors regulating mucosal wound healingInflammatory bowel disease (IBD) currently afflicts more than 3.1 million people in the U.S. with over 100,000 new cases each year. Patients with IBD experience persistent and relapsing gastrointestinal tract...
The postdoctoral training period is nearly essential for all research scientists who aspire to lead a research laboratory in a university or non-profit research center. To characterize the transition of scientists from postdoc to established PI, we previously conducted an analysis of how many postdocs with a NIH-sponsored F32 fellowship went on to become PIs of a R-esearch grant. In 2006, NIH int...
Previously, we calculated the fraction of the R01 grant pool that each institution has obtained in 2013, and how this fraction has changed over time. We now wanted to perform a complementary analysis, determining institutional variability in the length of time that individual PIs are able to maintain NIH grant funding. This analysis would be of interest to university administrators who want to rec...
In our database, for any grant we report "Related Projects" that are renewals of ongoing projects from individual investigators. We wanted to improve this by identifying "Related Projects" more generally in which we group different grants based on the text in the abstract. We analyzed the similarities of 2013 NIH grant abstracts with lengths of at least 100 words (disregarding the public health r...
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