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Cardiomyopathy in AIDS
Lewis, William / Emory University

This project elucidates mechanisms of dilated cardiomyopathy (DCM) in AIDS. Cardiac infection with human immunodeficiency virus-1 (HIV-1), intramyocardial activity of HIV-1 proteins, and toxicity from antiretroviral agents each is postulated...

R-Activated Protein C (APC) Dose Ranging Study in Hereditary Protein C Deficiency
Bauer, Kenneth /

This study will determine the intravenous infusion rate of r-activated protein C and plasma concentration of APC that reduces markers of activated coagulation in patients with hereditary protein C deficiency....

Treatment of Familial Hypercholesterolemia by Plasma Exchange
Ostlund, Richard E. / Washington University

2nd Microtherm Workshop and Tutorial to be held June 13-14, 1998 in Albuquerque, New Mexico
Chen, Gang; Majumdar, Arunava; Tien, Chang-Lin / University of California-Los Angeles

Abstract - Gang Chen 9813486 The goal of this workshop and tutorial is to provide a cross-disciplinary forum for discussion, education, and presentation of the latest results in the rapidly...

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Circadian Rhythms and Innate Immune Response in Aging
Fikrig, Erol; Shaw, Albert C. / Yale University

Circadian rhythms play crucial roles in a wide range of physiologic and behavioral processes. In mammals, variations in light intensity and other environmental cues are integrated by a master pacemaker...

AgTRIO, a protein in mosquito saliva, influences Plasmodium sporozoite infection
Fikrig, Erol / Yale University

Malaria is a global infectious disease that causes profound morbidity and mortality. RTS,S - currently the most advanced malaria vaccine ? is based upon the Plasmodium circumsporozoite protein (CSP) in...

Long Acting Film Technology for Contraception and HIV Prevention (LATCH)
Rohan, Lisa Cencia / Magee-Women's Research Institute and Foundation

Several studies (ASPIRE, VOICE) have shown that adherence is paramount to the success of HIV prevention methods in women. Providing women with options through alternative drug delivery technologies can positively...

How immunodominant Fc peptide epitopes expand natural regulatory T cells and downregulate inflammation
Franco, Alessandra I. / University of California, San Diego

Recently, we characterized a natural regulatory T cell (nTreg) lineage that recognizes the heavy constant region of immunoglobulin (Fc) very important in down-sizing the inflammation. Fc-specific nTreg can be found...


Latest in Grantomics:

In it to win it
Pathway to scientific independence by the NIH K99 award

In it to win it

The postdoctoral training period is nearly essential for all research scientists who aspire to lead a research laboratory in a university or non-profit research center. To characterize the transition of scientists from postdoc to established PI, we previously conducted an analysis of how many postdocs with a NIH-sponsored F32 fellowship went on to become PIs of a R-esearch grant. In 2006, NIH int...

Odds of success
Survival analysis of NIH grant applicants at top institutions

Odds of success

Previously, we calculated the fraction of the R01 grant pool that each institution has obtained in 2013, and how this fraction has changed over time. We now wanted to perform a complementary analysis, determining institutional variability in the length of time that individual PIs are able to maintain NIH grant funding. This analysis would be of interest to university administrators who want to rec...

The Perfect Blueprint
Abstract similarities across many grants

The Perfect Blueprint

In our database, for any grant we report "Related Projects" that are renewals of ongoing projects from individual investigators. We wanted to improve this by identifying "Related Projects" more generally in which we group different grants based on the text in the abstract. We analyzed the similarities of 2013 NIH grant abstracts with lengths of at least 100 words (disregarding the public health r...

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