. Statetheapplication's broad,long-termobjectivesandspecificaims, makingreference tothe healthrelatednessoftheproject.Describe concisely the research design and methodsfor achievingthese goals.Avoid summaries of past accomplishments andthe useof thefirst person.This description is meant to serve as a succinct and accuratedescription of the proposedwork when separated from the application. If the application is funded, this description, as is, will become public information. Therefore, do not include proprietary/confidential information. DO NOT EXCEED THE SPACE PROVIDED. We propose a multidisciplinary training program in environmental health in the following countries; Romania, Russia, Uzbekistan, Mongolia, Kenya and Uganda. The activities with Romania, Russia, Kenya and Uganda are continuations of ongoing Fogarty support from either our original grant, or from supplemental awards we have received. Uzbekistan and Mongolia are proposed as new countries to our Fogarty program, and we currently have students in Albany from these countries, supported by other funds, and are responding to requests from universities in these countries to be included. While the primary countries in our original award were Poland, Hungary and the Czech Republic, the economic and scientific progress there has been such that we believe our focus should be on countries of greater need for training in environmental health. However by maintaining programs in the Eastern European region, we will not lose our valuable relationships that have been established over the past six years in these more developed countries. The six countries in this application have very severe environmental health issues, and lack the resources, infrastructure and trained personnel to adequately deal with them. The issues of greatest importance in these countries are provision of drinking water and food that is not contaminated with either infectious or toxic substances, safe disposal of sewage, solid and hazardous wastes and air pollution. We propose a training program with an Albany-based faculty of epidemiologists, statisticians, toxicologists, water experts, ecologists, environmental chemists and remediation experts. Most of our funds will initially be expended on long-term (at least one year) training and research in Albany. Selected fellows will stay to complete a degree program. As trainees return to their home countries, we will support collaborative research with selected fellows. In addition we will mount one short-course each year in one of these countries on a topic chosen in consultation with the collaborating faculty there. PERFORMANCE SITE(S) (organization, city, state) School of Public Health, University at Albany, Albany, New York Makerere University,- Kampala, Uganda Environmental Health Center, Clui Naooca, Romania African Virtual University Centre at Egerton University, Njoro, Kenya Institute of Public Health, Ulaanbaatar, Mongolia Academy of Sciences of the Republic of Uzbekistan, Uzbekistan Tula State University, Tula, Russia KEY PERSONNEL. See instructions on Page 11. Use continuation pages as neededto provide the required Name Organization Carpenter, David O. University at Albany Arcaro, Kathleen University at Albany Birman, Irina University at Albany & NYS Dept. of Health DeCaprio, Anthony P. University at Albany Druschel, Charlotte University at Albany & NYS Dept. of Health Fitzgerald, Edward University at Albany Scrudato, Ronald SUNY Oswego Sokol, Roger University at Albany & NYS Dept. of Health Spink, David University at Albany & NYS Dept. of Health Zurbenko, Igor University at Albany Fayziev, Dilorom Acad. of Sci. of the Republic of Uzbekistan Githeko, Jason African Virtual Univ. Centre at Egerton Univ. Gurzau, Eugen Environmental Health Centres Kachurin, Nikolai Tula State University Muganwa, Margaret Makerere University Narantuya Sodnom Institute of Public Health PHS 398 (Rev.""""""""4/98) Page 2 Number pages consecutively at the bottom throughout the application. Do noJuse suffixes such as 3a, 3b. information in the format shown below. Role on Project Principal Investigator Co-Investigator Co-lnvestigato Co-Investigator Co-Investigator Co-Investigator Co-Investigator Co-Investigator .Co-Investigator Co-Investigator Major Foreign Collaborator Major Foreign Collaborator Major Foreign Collaborator Major Foreign Collaborator Major Foreign Collaborator Major Foreign Collaborator BB tf Principal Wcstigator/Program Director (Last, first, middle): C^Bpenter, David OrlO

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
International Research Training Grants (D43)
Project #
3D43TW000636-10S1
Application #
7229379
Study Section
Special Emphasis Panel (ZES1)
Program Officer
Schonwalder, Chris
Project Start
1995-09-30
Project End
2007-04-30
Budget Start
2005-05-01
Budget End
2007-04-30
Support Year
10
Fiscal Year
2006
Total Cost
$150,000
Indirect Cost
Name
State University of New York at Albany
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
152652822
City
Albany
State
NY
Country
United States
Zip Code
12222
Smolyaninova, Larisa V; Dergalev, Alexander A; Kulebyakin, Konstantin Y et al. (2013) Carnosine prevents necrotic and apoptotic death of rat thymocytes via ouabain-sensitive Na/K-ATPase. Cell Biochem Funct 31:30-5
Sergeev, Alexander V; Carpenter, David O (2011) Increase in metabolic syndrome-related hospitalizations in relation to environmental sources of persistent organic pollutants. Int J Environ Res Public Health 8:762-76
Sergeev, Alexander V; Carpenter, David O (2011) Geospatial patterns of hospitalization rates for stroke with comorbid hypertension in relation to environmental sources of persistent organic pollutants: results from a 12-year population-based study. Environ Sci Pollut Res Int 18:576-85
Sergeev, Alexander V; Carpenter, David O (2010) Increased hospitalizations for ischemic stroke with comorbid diabetes and residential proximity to sources of organic pollutants: a 12-year population-based study. Neuroepidemiology 35:196-201
Sergeev, Alexander V; Carpenter, David O (2010) Residential proximity to environmental sources of persistent organic pollutants and first-time hospitalizations for myocardial infarction with comorbid diabetes mellitus: a 12-year population-based study. Int J Occup Med Environ Health 23:5-13
Sergeev, Alexander V; Carpenter, David O (2010) Exposure to Persistent Organic Pollutants Increases Hospitalization Rates for Myocardial Infarction with Comorbid Hypertension. Prim Prev Insights 2:1-9
Ssempebwa, John C; Carpenter, David O (2009) The generation, use and disposal of waste crankcase oil in developing countries: a case for Kampala district, Uganda. J Hazard Mater 161:835-41
Goncharov, Alexey; Rej, Robert; Negoita, Serban et al. (2009) Lower serum testosterone associated with elevated polychlorinated biphenyl concentrations in Native American men. Environ Health Perspect 117:1454-60
Neagu, Bogdan; Strominger, Norman L; Carpenter, David O (2008) Contribution of NMDA receptor-mediated component to the EPSP in mouse Schaffer collateral synapses under single pulse stimulation protocol. Brain Res 1240:54-61
Goncharov, Alexey; Haase, Richard F; Santiago-Rivera, Azara et al. (2008) High serum PCBs are associated with elevation of serum lipids and cardiovascular disease in a Native American population. Environ Res 106:226-39

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