Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
International Research Training Grants (D43)
Project #
5D43TW000671-04
Application #
2797151
Study Section
Special Emphasis Panel (SRC (TW))
Project Start
1995-09-30
Project End
2000-09-29
Budget Start
1998-09-30
Budget End
1999-09-29
Support Year
4
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Rodriguez Peña, Marcelo J; Castillo Bennett, Jimena V; Soler, Osvaldo M et al. (2013) MARCKS protein is phosphorylated and regulates calcium mobilization during human acrosomal exocytosis. PLoS One 8:e64551
Muro, Yuko; Buffone, Mariano G; Okabe, Masaru et al. (2012) Function of the acrosomal matrix: zona pellucida 3 receptor (ZP3R/sp56) is not essential for mouse fertilization. Biol Reprod 86:1-6
Buffone, Mariano G; Kim, Kye-Seong; Doak, Birgit J et al. (2009) Functional consequences of cleavage, dissociation and exocytotic release of ZP3R, a C4BP-related protein, from the mouse sperm acrosomal matrix. J Cell Sci 122:3153-60
Buffone, Mariano G; Rodriguez-Miranda, Esmeralda; Storey, Bayard T et al. (2009) Acrosomal exocytosis of mouse sperm progresses in a consistent direction in response to zona pellucida. J Cell Physiol 220:611-20
Buffone, Mariano G; Schindler, Karen; Schultz, Richard M (2009) Overexpression of CDC14B causes mitotic arrest and inhibits zygotic genome activation in mouse preimplantation embryos. Cell Cycle 8:3904-13
Buckanovich, Ronald J; Facciabene, Andrea; Kim, Sarah et al. (2008) Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy. Nat Med 14:28-36
Buffone, Mariano G; Foster, James A; Gerton, George L (2008) The role of the acrosomal matrix in fertilization. Int J Dev Biol 52:511-22
Benencia, Fabian; Courreges, Maria C; Fraser, Nigel W et al. (2008) Herpes virus oncolytic therapy reverses tumor immune dysfunction and facilitates tumor antigen presentation. Cancer Biol Ther 7:1194-205
Rodriguez-Miranda, Esmeralda; Buffone, Mariano G; Edwards, Scott E et al. (2008) Extracellular adenosine 5'-triphosphate alters motility and improves the fertilizing capability of mouse sperm. Biol Reprod 79:164-71
Buffone, Mariano G; Zhuang, Tiangang; Ord, Teri S et al. (2008) Recombinant mouse sperm ZP3-binding protein (ZP3R/sp56) forms a high order oligomer that binds eggs and inhibits mouse fertilization in vitro. J Biol Chem 283:12438-45

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