The Malaria Section at the Center for Vaccine Development (CVD), University of Maryland School of Medicine has been providing training opportunities for scientists from African and Latin American countries for several years. The Malaria Research and Training Center (MRTC) at the University of Malaria also has extensive training experience, and is widely recognized as a center of excellence in Africa for malaria research and training in malaria research and control. We propose to build on this diverse and extensive training experience to develop a formal malaria research training program in a close collaboration with the MRTC, in the context of an ongoing research project supported by contract N01-AI- 85346 from NIAID, funded through September 2003. This project has a substantial field component, and training will be available in clinical trials, epidemiology and biostatistics, molecular biology, immunology, and entomology. Training will take place in both the U.S. and Malaria. Training faculty and facilities will be drawn from the CVD and MRTC as well as from collaborating laboratories and institutions. Training will be provided to: 1) Junior researchers at MRTC who are completing or have recently completed M.D. or Pharm.D. degrees at the University of Mali School of Medicine, Pharmacy and Dentistry; and 2) MRTC post-doctoral researchers who have recently completed Ph.D. studies in the U.S. or Europe and are attempting to establish their research programs. The first group will enroll in Master's or Ph.D. programs at the University of Mali. Four of these student trainees will spend 9 months each year receiving hands-on research training in Mali, under the supervision of Malian and U.S. training faculty, and 3 months each year in the U.S. receiving didactic and/or practical research training. The post-doctoral researchers will be supported by direct research mentoring and collaboration with U.S. and Malian training faculty and by provision of start-up funds to purchase supplies or small equipment or support field activities to generate preliminary data that will form the basis for applying for external grant funding.

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
International Research Training Grants (D43)
Project #
3D43TW001589-05S1
Application #
6916889
Study Section
Special Emphasis Panel (ZAI1)
Program Officer
Primack, Aron
Project Start
2000-09-29
Project End
2005-02-28
Budget Start
2004-03-01
Budget End
2005-02-28
Support Year
5
Fiscal Year
2004
Total Cost
$50,000
Indirect Cost
Name
University of Maryland Baltimore
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
188435911
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Niangaly, Amadou; Karthigayan Gunalan; Amed Ouattara et al. (2017) Plasmodium vivax Infections over 3 Years in Duffy Blood Group Negative Malians in Bandiagara, Mali. Am J Trop Med Hyg 97:744-752
Dara, Antoine; Travassos, Mark A; Adams, Matthew et al. (2017) A new method for sequencing the hypervariable Plasmodium falciparum gene var2csa from clinical samples. Malar J 16:343
Dara, Antoine; Drábek, Elliott F; Travassos, Mark A et al. (2017) New var reconstruction algorithm exposes high var sequence diversity in a single geographic location in Mali. Genome Med 9:30
Graves, Shawna F; Kouriba, Bourema; Diarra, Issa et al. (2016) Strain-specific Plasmodium falciparum multifunctional CD4(+) T cell cytokine expression in Malian children immunized with the FMP2.1/AS02A vaccine candidate. Vaccine 34:2546-55
Sobota, Rafal S; Dara, Antoine; Manning, Jessica E et al. (2016) Expression of complement and toll-like receptor pathway genes is associated with malaria severity in Mali: a pilot case control study. Malar J 15:150
Nabet, Cécile; Doumbo, Safiatou; Jeddi, Fakhri et al. (2016) Genetic diversity of Plasmodium falciparum in human malaria cases in Mali. Malar J 15:353
Malaria Genomic Epidemiology Network; Band, Gavin; Rockett, Kirk A et al. (2015) A novel locus of resistance to severe malaria in a region of ancient balancing selection. Nature 526:253-7
Travassos, Mark A; Coulibaly, Drissa; Bailey, Jason A et al. (2015) Differential recognition of terminal extracellular Plasmodium falciparum VAR2CSA domains by sera from multigravid, malaria-exposed Malian women. Am J Trop Med Hyg 92:1190-4
Bailey, Jason A; Pablo, Jozelyn; Niangaly, Amadou et al. (2015) Seroreactivity to a large panel of field-derived Plasmodium falciparum apical membrane antigen 1 and merozoite surface protein 1 variants reflects seasonal and lifetime acquired responses to malaria. Am J Trop Med Hyg 92:9-12
Ouattara, Amed; Kone, Aminatou; Adams, Matthew et al. (2015) Polymorphisms in the K13-propeller gene in artemisinin-susceptible Plasmodium falciparum parasites from Bougoula-Hameau and Bandiagara, Mali. Am J Trop Med Hyg 92:1202-6

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