Mechanism of N-Nitrosodiethanolamine Carcinogensis

Loeppky, Richard N.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: Fogarty International Center (FIC)
• Type: Unknown (F06)
• Project #: 1F06TW001944-01A1
• Application #: 2292428
• Study Section: Biomedical Sciences Study Section (BIOM)
• Project Start: 1994-09-29
• Budget Start: 1993-10-01
• Budget End: 1994-08-31
• Support Year: 1
• Fiscal Year: 1993

Institution

• Name: University of Missouri-Columbia
• Department: Chemistry
• Type: Schools of Arts and Sciences
• DUNS #: 112205955
• City: Columbia
• State: MO
• Country: United States
• Zip Code: 65211

Publications

Loeppky, R N (1999) The mechanism of bioactivation of N-nitrosodiethanolamine. Drug Metab Rev 31:175-93

Loeppky, R N; Fuchs, A; Janzowski, C et al. (1998) Probing the mechanism of the carcinogenic activation of N-nitrosodiethanolamine with deuterium isotope effects: in vivo induction of DNA single-strand breaks and related in vitro assays. Chem Res Toxicol 11:1556-66