The Retrovirus Research Center (RRC) is a facility that promote and stimulates research addressing the HIV and AIDS epidemic in Puerto Rico. The RRC is composed of a Leadership Core and a Laboratory Core. In addition it works intimately with the Data Management and Statistical Research Support Unit (DMSRSU), which manages a longitudinal database of over 4,000 patients with HIV infection. It's considered unique in Puerto Rico since it is the only one in which full Integration of the research effort with the health care delivery facility is In place.
The aim of the RRC Is to promote the study of HIV- Infection as a multidisciplinary research arena In which the clinical, immunological, virological, psychosocial and behavioral parameters need to be integrated Into a coherent research strategy. The center agglutinates multidisciplinary researchers Interesting In describing and understanding key elements of HIV infection according to an ecological view. The RRC has an important role In continuing the research agenda with this patient population with the goal of diminishing the spreading nature of the HIV epidemic In the Island. The Leadership Core coordinates and facilitates an Intellectually stimulating environment for HIV/AIDS research by playing a proactive role In generating hypothesis-driven studies. This multidisciplinary vision of the RRC is responsive to the vision of the National Institutes of Health their role of studying the complexity of diseases. Our objectives for the next five years will Include 1. Provide the support for the study of the multidimensional aspects of HIV Infection, by planning and stimulating HIV/AIDS research, scientific productivity and hypothesis driven studies. 2. Provide support for HIV research activities. The resources Include the HIV Data Registry, the specialized laboratory and the plasma and lymphocyte repository. 3. Contribute to the research development career of the RRC faculty members and research staff in coordination with the DMSRSU and the SRDU. 4. Continue to provide support for community Involvement In research activities. 5. Develop strategies to become a RCMI Independent HIV Research Center.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Research Centers in Minority Institutions Award (G12)
Project #
3G12MD007583-28S2
Application #
9281281
Study Section
Special Emphasis Panel (ZRR1)
Program Officer
Zhang, Xinzhi
Project Start
2016-07-01
Project End
2017-06-30
Budget Start
2016-07-01
Budget End
2017-06-30
Support Year
28
Fiscal Year
2016
Total Cost
Indirect Cost
Name
Universidad Central Del Caribe
Department
Type
DUNS #
090534694
City
Bayamon
State
PR
Country
United States
Zip Code
Grover, Surbhi; Desir, Fidel; Jing, Yuezhou et al. (2018) Reduced Cancer Survival Among Adults With HIV and AIDS-Defining Illnesses Despite No Difference in Cancer Stage at Diagnosis. J Acquir Immune Defic Syndr 79:421-429
Yanik, Elizabeth L; Hernández-Ramírez, Raúl U; Qin, Li et al. (2018) Brief Report: Cutaneous Melanoma Risk Among People With HIV in the United States and Canada. J Acquir Immune Defic Syndr 78:499-504
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Serrano-Negrón, Jesús E; Zhang, Zhenbo; Rivera-Ruiz, Andrea P et al. (2018) Tunicamycin-induced ER stress in breast cancer cells neither expresses GRP78 on the surface nor secretes it into the media. Glycobiology 28:61-68
Morales-Ortíz, Jessica; Deal, Victoria; Reyes, Fiorella et al. (2018) Platelet-derived TLT-1 is a prognostic indicator in ALI/ARDS and prevents tissue damage in the lungs in a mouse model. Blood 132:2495-2505
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Karl, Anett; Agte, Silke; Zayas-Santiago, Astrid et al. (2018) Retinal adaptation to dim light vision in spectacled caimans (Caiman crocodilus fuscus): Analysis of retinal ultrastructure. Exp Eye Res 173:160-178
Agte, Silke; Savvinov, Alexey; Karl, Anett et al. (2018) Müller glial cells contribute to dim light vision in the spectacled caiman (Caiman crocodilus fuscus): Analysis of retinal light transmission. Exp Eye Res 173:91-108
Rodríguez-Valentín, Madeline; López, Sheila; Rivera, Mariela et al. (2018) Naturally Derived Anti-HIV Polysaccharide Peptide (PSP) Triggers a Toll-Like Receptor 4-Dependent Antiviral Immune Response. J Immunol Res 2018:8741698
AIDS-defining Cancer Project Working Group of IeDEA, COHERE in EuroCoord (2018) Non-Hodgkin lymphoma risk in adults living with HIV across five continents. AIDS 32:2777-2786

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