The proposed program will focus on research related to diseases which have a high incidence in urban blacks. Although research projects will include initiatives in Chemistry, Biology and Pharmacy, the greatest emphasis will be placed on increasing the overall research capability in the pharmaceutical sciences. In order to achieve the overall program goals, funds are requested over a five year period to cover the following activities: a) The improvement of faculty research capability. b) The support of individual projects which fall within the scope of the proposed center. c) The establishment and support of an Office for Research Resources in Biomedicine. d) The recruitment of new research faculty and support of their research project in Pharmacy and Health Sciences. e) The provision for hiring technical personnel in animal care and equipment maintenance. f) The implementation of a reliable evaluation design for the proposed program. g) The acquisition of support equipment. The University will demonstrate its commitment to this effort by purchasing equipment, supporting faculty development, improving the reward system for productive research and by establishing endowed chairs in Chemistry and Pharmaceutical Sciences. The university will also assume support of the new faculty by phasing them into its regular program.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Research Centers in Minority Institutions Award (G12)
Project #
5G12RR003045-03
Application #
3058777
Study Section
(SRC)
Project Start
1986-09-30
Project End
1991-09-29
Budget Start
1988-09-30
Budget End
1989-09-29
Support Year
3
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Texas Southern University
Department
Type
Schools of Pharmacy
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77004
Oloyo, Ahmed K; Sofola, Olusoga A; Yakubu, Momoh A (2016) Orchidectomy attenuates high-salt diet-induced increases in blood pressure, renovascular resistance, and hind limb vascular dysfunction: role of testosterone. Clin Exp Pharmacol Physiol 43:825-33
Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Adedapo, Adeolu Alex et al. (2016) Kolaviron, Biflavonoid Complex from the Seed of Garcinia kola Attenuated Angiotensin II- and Lypopolysaccharide-induced Vascular Smooth Muscle Cell Proliferation and Nitric Oxide Production. Pharmacognosy Res 8:S50-5
Liang, Su; Bian, Xiaomei; Liang, Dong et al. (2016) Solution formulation development and efficacy of MJC13 in a preclinical model of castration-resistant prostate cancer. Pharm Dev Technol 21:121-6
Robinson, Keila; Mock, Charlotta; Liang, Dong (2015) Pre-formulation studies of resveratrol. Drug Dev Ind Pharm 41:1464-9
Wang, Yan; Ye, Yuanqing; Lin, Jie et al. (2015) Genetic variants in matrix metalloproteinase genes as disposition factors for ovarian cancer risk, survival, and clinical outcome. Mol Carcinog 54:430-9
Liang, Su; Sanchez-Espiridion, Beatriz; Xie, Huan et al. (2015) Determination of proline in human serum by a robust LC-MS/MS method: application to identification of human metabolites as candidate biomarkers for esophageal cancer early detection and risk stratification. Biomed Chromatogr 29:570-7
Jimenez, Angelica; Adisa, Afolabi; Woodham, Cara et al. (2014) Determination of polycyclic aromatic hydrocarbons in roasted coffee. J Environ Sci Health B 49:828-35
Bell, Edward C; John, Mathew; Hughes, Rodney J et al. (2014) Ultra-performance liquid chromatographic determination of tocopherols and retinol in human plasma. J Chromatogr Sci 52:1065-70
Meng, Qing H; Xu, Enping; Hildebrandt, Michelle A T et al. (2014) Genetic variants in the fibroblast growth factor pathway as potential markers of ovarian cancer risk, therapeutic response, and clinical outcome. Clin Chem 60:222-32
Liang, Su; Bian, Xiaomei; Sivils, Jeffrey et al. (2014) Quantification of a New Anti-Cancer Molecule MJC13 Using a Rapid, Sensitive, and Reliable Liquid Chromatography-Tandem Mass Spectrometry Method. Am J Mod Chromatogr 1:1-11

Showing the most recent 10 out of 46 publications