This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.The Biosensor and Biomarker Technology (BBT) Core Facility is a research support facility that exists to provide technical and resources support and hands-on training in molecular and biochemical techniques for investigators engaged in environmental and biomedical research at Texas Southern University. The main objective of the BBT is to provide essential research infrastructure to improve and facilitate the research capabilities of faculty investigators and graduate students. To accomplish these goals, the BBT core facility provides methods development for novel biosensing techniques to detect toxicants; analytical methodology for xenobiotics and environmental pollutants; computer aided molecular design, modeling and quantitative analysis of structure activity relationships; and high resolution printing and imaging preparation for scientific publications.
The specific aims of the BBT Core Facility are to:1. Continue to provide special training and technical support in biomarker research, particularly in areas of molecular biology, biotechnology, environmental toxicology, and instrumental analytical techniques, as well as high-resolution printing and imaging services, to investigators to facilitate their specific research projects.2. Implement new training and technical services through the Biosensor component to help TSU faculty and graduate students take advantage of the state-of-the-art biosensor technology to pursue advanced biomedical and environmental research goals.3. Provide appropriate research infrastructure to foster new research programs among interested TSU investigators. 4. Promote the organization of and participation in seminars focusing on biosensor technology, electroanalytical techniques, biomarker technology, and advances in environmental toxicology. 5. Create a research-friendly environment that leads to multidisciplinary study, efficient teamwork and collaboration, higher research productivity, and effective information exchange within and outside of the TSU campus.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Research Centers in Minority Institutions Award (G12)
Project #
5G12RR003045-21
Application #
7715329
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2008-08-01
Project End
2013-07-31
Budget Start
2008-08-01
Budget End
2009-07-31
Support Year
21
Fiscal Year
2008
Total Cost
$331,418
Indirect Cost
Name
Texas Southern University
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
050298975
City
Houston
State
TX
Country
United States
Zip Code
77004
Oloyo, Ahmed K; Sofola, Olusoga A; Yakubu, Momoh A (2016) Orchidectomy attenuates high-salt diet-induced increases in blood pressure, renovascular resistance, and hind limb vascular dysfunction: role of testosterone. Clin Exp Pharmacol Physiol 43:825-33
Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Adedapo, Adeolu Alex et al. (2016) Kolaviron, Biflavonoid Complex from the Seed of Garcinia kola Attenuated Angiotensin II- and Lypopolysaccharide-induced Vascular Smooth Muscle Cell Proliferation and Nitric Oxide Production. Pharmacognosy Res 8:S50-5
Liang, Su; Bian, Xiaomei; Liang, Dong et al. (2016) Solution formulation development and efficacy of MJC13 in a preclinical model of castration-resistant prostate cancer. Pharm Dev Technol 21:121-6
Robinson, Keila; Mock, Charlotta; Liang, Dong (2015) Pre-formulation studies of resveratrol. Drug Dev Ind Pharm 41:1464-9
Wang, Yan; Ye, Yuanqing; Lin, Jie et al. (2015) Genetic variants in matrix metalloproteinase genes as disposition factors for ovarian cancer risk, survival, and clinical outcome. Mol Carcinog 54:430-9
Liang, Su; Sanchez-Espiridion, Beatriz; Xie, Huan et al. (2015) Determination of proline in human serum by a robust LC-MS/MS method: application to identification of human metabolites as candidate biomarkers for esophageal cancer early detection and risk stratification. Biomed Chromatogr 29:570-7
Jimenez, Angelica; Adisa, Afolabi; Woodham, Cara et al. (2014) Determination of polycyclic aromatic hydrocarbons in roasted coffee. J Environ Sci Health B 49:828-35
Bell, Edward C; John, Mathew; Hughes, Rodney J et al. (2014) Ultra-performance liquid chromatographic determination of tocopherols and retinol in human plasma. J Chromatogr Sci 52:1065-70
Meng, Qing H; Xu, Enping; Hildebrandt, Michelle A T et al. (2014) Genetic variants in the fibroblast growth factor pathway as potential markers of ovarian cancer risk, therapeutic response, and clinical outcome. Clin Chem 60:222-32
Liang, Su; Bian, Xiaomei; Sivils, Jeffrey et al. (2014) Quantification of a New Anti-Cancer Molecule MJC13 Using a Rapid, Sensitive, and Reliable Liquid Chromatography-Tandem Mass Spectrometry Method. Am J Mod Chromatogr 1:1-11

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