The Biostatistical Laboratory continues to provide statistical consulting to Center participants and the local biomedical community. During the present cycle of funding, efforts were made to contact and visit the local clinicians, hospitals and other health care institutions, and to inform them of the facilities and statistical consulting services available through the Biostatistical Laboratory. As a result of these efforts several projects involving clinicians and consultants in the Laboratory have resulted. Interdisciplinary research in the areas of Nonparametric Survival Analysis with order constraints imposed by experimental conditions and Mathematical and Statistical problems in Molecular Biology continue to be the focus of the research efforts of the faculty associated with the Biostatistical Laboratory. These efforts have produced 19 refereed publications, 6 technical reports, and 13 publications under review. Several proposals are under preparation and 2 have been submitted. The strong BioStatistics seminar continues with great success having invited 23 top researchers in the areas of survival analysis and problems in molecular biology. Efforts also continue in attracting promising postdoctoral students to interact with the BioStatistics Laboratory faculty. The computing facilities continue to be upgraded to provide state-of-the-art facilities and software for the consulting and research missions of the laboratory.

Project Start
Project End
Budget Start
Budget End
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Cox, Marc B; Johnson, Jill L (2018) Evidence for Hsp90 Co-chaperones in Regulating Hsp90 Function and Promoting Client Protein Folding. Methods Mol Biol 1709:397-422
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Sobin, Christina; Flores-Montoya, Mayra Gisel; Alvarez, Juan Manuel (2017) Early chronic low-level Pb exposure alters global exploratory behaviors but does not impair spatial and object memory retrieval in an object-in-place task in pre-adolescent C57BL/6J mice. Neurotoxicol Teratol 61:104-114
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Iniguez, Eva; Schocker, Nathaniel S; Subramaniam, Krishanthi et al. (2017) An ?-Gal-containing neoglycoprotein-based vaccine partially protects against murine cutaneous leishmaniasis caused by Leishmania major. PLoS Negl Trop Dis 11:e0006039
Zimkus, Breda M; Lawson, Lucinda P; Barej, Michael F et al. (2017) Leapfrogging into new territory: How Mascarene ridged frogs diversified across Africa and Madagascar to maintain their ecological niche. Mol Phylogenet Evol 106:254-269
Dai, Liping; Peng, Xuan-Xian; Tan, Eng M et al. (2016) Tumor-associated antigen CAPER? and microvessel density in hepatocellular carcinoma. Oncotarget 7:16985-95

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