Abstract

The goal of this project is to develop three types of immunosensors for cocaine and cortisol which is an indicator of adrenal function. Those techniques involve using immobilized antibodies in conjunction with piezoelectric, fiber optic and electro-chemical transducers. Last year goals were to study and compare the immobilization techniques, optimize the various variables affecting the piezoelectric immunosensors for the respective analytes were developed and two manuscripts were submitted for publication. Currently we are investigating the fiber optic sensor for cortisol and cocaine. Cortisol results for encouraging.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Research Centers in Minority Institutions Award (G12)
Project #
3G12RR009104-05S1
Application #
6122956
Study Section
Project Start
1997-09-30
Project End
2000-09-29
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
5
Fiscal Year
1998
Total Cost
Indirect Cost

  Institution

Name
Southern University A&M Col Baton Rouge
Department
Type
DUNS #
City
Baton Rouge
State
LA
Country
United States
Zip Code
70813

  Publications

Tate, T M; Jackson, R N; Christian, F A (2000) Effects of glyphosate and dalapon on total free amino acid profiles of Pseudosuccinea columella snails. Bull Environ Contam Toxicol 64:258-62
Owens, J W; Robins, M; Robinson, R et al. (1996) Chromatographic analysis of photodynamically significant porphyrin dimers and trimers. J Chromatogr B Biomed Appl 682:327-36
Owens, J W; Yang, L; Adeola, G et al. (1995) Isolation and photodynamic effects of hematoporphyrin derivative components: a chromatographic analysis of the starting materials. J Chromatogr B Biomed Appl 669:295-309