Although Written Exposure Therapy (WET) is listed in the upcoming VA/DoD PTSD Practice Guidelines as an evidence-based, recommended PTSD treatment, there are limited data supporting the use of WET with veterans suffering from PTSD. Additional research is needed to support the use of WET for the treatment of veterans diagnosed with PTSD. The goal of this study is to investigate whether WET is non-inferior in the treatment of PTSD in a sample of veterans diagnosed with PTSD. Men and women veterans diagnosed with PTSD will be randomly assigned to either WET (n = 75) or Prolonged Exposure (PE; n = 75). PTSD symptom severity will serve as the primary outcome. Assessments will be conducted by independent evaluators at baseline, 10-, 20-, and 20-week post first treatment session. WET is expected to be non-inferior to PE in reducing PTSD symptom severity. In addition, WET is expected to have significantly lower treatment dropout rate relative to the first five sessions of PE (i.e., better treatment engagement). Moderators of treatment outcome for both treatment conditions will also be investigated. If WET is found to be non-inferior to the more time intensive PE treatment then the VA will have evidence to support the use of a brief PTSD treatment, which will assist in addressing the high demand for PTSD clinical services.

Public Health Relevance

PTSD is a prevalent condition for which veterans frequently seek treatment in the VA healthcare system. Although there are several first-line PTSD treatments available, at least one third of veterans drop out prematurely from these treatments. Further, VA mental health treatment providers have noted numerous systemic barriers to implementing these treatments with their veteran clients. These problems underscore the need to identify alternative, evidence-based treatments that address both patient and provider concerns. Written Exposure Therapy (WET) may be such a treatment. If WET is found efficaciously treat veterans with PTSD, then VA would have a brief and well-tolerated PTSD treatment option for use with veterans.

Agency
National Institute of Health (NIH)
Institute
Veterans Affairs (VA)
Type
Non-HHS Research Projects (I01)
Project #
1I01CX001967-01
Application #
9779211
Study Section
Special Emphasis Panel (ZRD1)
Project Start
2019-07-01
Project End
2024-06-30
Budget Start
2019-07-01
Budget End
2020-06-30
Support Year
1
Fiscal Year
2019
Total Cost
Indirect Cost
Name
VA Boston Health Care System
Department
Type
DUNS #
034432265
City
Boston
State
MA
Country
United States
Zip Code
02130