Our goal, as defined in this renewal of our career development program, entitled Building Interdisciplinary Research Careers in Women's Health in Pittsburgh (BIRCWH@Pitt), is to build on our success to train, nurture, and support talented University of Pittsburgh (Pitt) faculty scholars in personalized prevention, diagnostics, and therapeutics for girls and women. We have built our program on an unparalleled strength in reproductive sciences and women's health research, led by Magee-Womens Research Institute (MWRI) within Pitt. MWRI is located at the center of Pitt's campus, and is immediately adjacent to Magee-Womens Hospital of the University of Pittsburgh Medical Center, one of the nation's most robust integrated healthcare systems. Our 98 researchers are fully engaged in basic, translational, behavioral, clinical, and health services research, pursued at Pitt's six health sciences schools and at MWRI's research facility. We strive to catalyze training and research in women's health locally, regionally, and nationally, promote the dissemination of our research to communities, and advocate for policies that promote personalized medicine to women and girls. With MWRI as the programmatic hub of BIRCWH@Pitt, we have markedly strengthened our women's health network and created new and exciting investigative nodes within Pitt's Clinical and Translational Science Institute (CTSI). We have also created a new core within Pitt's CTSI, designed to promote research on special populations, with a vanguard emphasis on women across the lifespan, including girls, adolescents, pregnant women, and postmenopausal and older individuals. These programs, as detailed in this application, represent a bold and far-reaching plan to include females of diverse ethnic groups or gender orientation and those living in rural communities or with disabilities. These recently established platforms enable us to focus on our long-term objectives of scholars' education, intellectual stimulation, hands-on training, intense career development toward full academic independence, motivation of new collaborative synergies, and implementation of sustainable women's health research. Cognizant of the fact that our scholars enter our program with diverse academic backgrounds and investigative skills, we have crafted individually tailored career development plans of 2-5 years, depending on each scholar's training and expertise. A team of mentors with diverse yet complementary skills is assembled, based on the scholar's background and needs, and works with each scholar to achieve her/his goals. Each scholar is guided by an interdisciplinary group of three mentors and overseen by an Advisory Committee comprised of researchers with heterogeneous scientific backgrounds. Resources garnered through our program are shared with other reproductive sciences trainees at MWRI and across Pitt's Health Sciences. Together, BIRCWH@Pitt emphasizes imaginative thinking, cross-fertilization, and collaboration that bridges basic sciences and clinical medicine, and serves to propel our scholars to successful careers in women's health and the dissemination of knowledge to academy and community.
Despite impressive scientific advances in recent years, the field of women's health research continues to lag behind the forefront of scientific development. We propose to take advantage of the extraordinary academic environment at Magee-Womens Research Institute and the University of Pittsburgh schools of Health Sciences to offer an exceptional interdisciplinary training program across a woman's lifespan, emphasizing personalized prevention, diagnostics, and therapeutics for girls and women.
| Lim, Grace; Facco, Francesca L; Nathan, Naveen et al. (2018) A Review of the Impact of Obstetric Anesthesia on Maternal and Neonatal Outcomes. Anesthesiology 129:192-215 |
| Hachim, Daniel; Brown, Bryan N (2018) Surface modification of polypropylene for enhanced layer-by-layer deposition of polyelectrolytes. J Biomed Mater Res A 106:2078-2085 |
| Lim, Grace; Kotsis, Eleni; Zorn, Jamie M et al. (2018) Cell salvage for postpartum haemorrhage during vaginal delivery: a case series. Blood Transfus 16:498-501 |
| Holliday, Charvonne N; Miller, Elizabeth; Decker, Michele R et al. (2018) Racial Differences in Pregnancy Intention, Reproductive Coercion, and Partner Violence among Family Planning Clients: A Qualitative Exploration. Womens Health Issues 28:205-211 |
| Jarlenski, Marian; Koma, Jonathan W; Zank, Jennifer et al. (2018) Media portrayal of prenatal and postpartum marijuana use in an era of scientific uncertainty. Drug Alcohol Depend 187:116-122 |
| Krans, Elizabeth E; Kim, Joo Yeon; James 3rd, Alton Everette et al. (2018) Postpartum contraceptive use and interpregnancy interval among women with opioid use disorder. Drug Alcohol Depend 185:207-213 |
| Spehar, Stephanie M; Mission, John F; Amanda Shupe et al. (2018) Prolonged antepartum hospitalization: no time for rest. J Perinatol 38:1151-1156 |
| Saunders, Jennifer B; Jarlenski, Marian P; Levy, Robert et al. (2018) Federal and State Policy Efforts to Address Maternal Opioid Misuse: Gaps and Challenges. Womens Health Issues 28:130-136 |
| Achilles, Sharon L; Mhlanga, Felix G; Musara, Petina et al. (2018) Misreporting of contraceptive hormone use in clinical research participants. Contraception 97:346-353 |
| Catov, Janet M; Snyder, Gabrielle G; Fraser, Abigail et al. (2018) Blood Pressure Patterns and Subsequent Coronary Artery Calcification in Women Who Delivered Preterm Births. Hypertension 72:159-166 |
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