This is a proposal to continue the Pediatric Critical Care Scientist Development Program (PCCSDP) as a national program (not institutional) to support research career development for young faculty in pediatric critical care. The program is extended by the RFA to include pediatric trauma surgery, and is renamed the Pediatric Critical Care and Trauma Scientist Development Program (PCCTSDP). The goal of the PCCTSDP is to increase the number of highly trained, successfully funded and sustainable physician scientists in pediatric critical care and trauma surgery, who will do translational research to enhance the scientific understanding of the pathophysiology and clinical management of critical illness and trauma, with emphasis on long-term consequences of critical illness and injury for children and families. In the first nine years of the program, 31 Scholars have been appointed, 14 have obtained their own K08 or K23 awards, and 2 have received R01 awards. The PCCTSDP awardees (Scholars) are selected by a National Advisory Committee (NAC) consisting of pediatric department chairs, outstanding scientists, and liaisons from the Society of Critical Care Medicine, the American Academy of Pediatrics, and the American Board of Pediatrics. Applicants will identify an outstanding scientific mentor, potentially at an institution separate from their fellowship training, and will be sponsored by their department chair. Each Scholar will spend 2 years in an intense research training environment, (usually in a basic science laboratory, but research selection is not limited to basic science), with a minimum of 75% protection from non-research responsibilities (Phase I). In the subsequent 3 years (for a total of 5 years), Scholars must be financially supported by their institutions and extramural funds, and must continue to have at least 50% - 75% protection to transition into independent investigators (Phase II). PCCTSDP conducts an annual scientific retreat during which Scholars will interact with the NAC members and NIH staff, present their scientific work, discuss their career development plans and progress, and participate in selected workshops on faculty development, grant writing, mock grant reviews, and other rele- vant topics. Each Scholar will submit a K or R award proposal before the end of the second year of support. By providing extended training and protected time to develop outstanding skills in these young faculties, the PCCTSDP will continue to increase the pool of skilled investigators in pediatric critical care and trauma.

Public Health Relevance

to Public Health Pediatric critical care and trauma physician-scientists and the knowledge and discoveries resulting from their research are vital for the health of children. The nation is facing a shortage of pediatric critical care and trauma physician scientists. The goal of the PCCTSDP is to increase the number of highly trained, successfully funded and sustainable physician scientists in pediatric critical care and trauma surgery, who will do translational research to enhance the scientific understanding of the pathophysiology and clinical management of critical illness and trauma, with emphasis on long-term consequences of critical illness and injury for children and families.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Physician Scientist Award (Program) (PSA) (K12)
Project #
5K12HD047349-14
Application #
9320023
Study Section
Special Emphasis Panel (ZHD1)
Program Officer
Tamburro, Robert F
Project Start
2004-08-23
Project End
2019-06-30
Budget Start
2017-07-01
Budget End
2018-06-30
Support Year
14
Fiscal Year
2017
Total Cost
Indirect Cost
Name
University of Utah
Department
Pediatrics
Type
Schools of Medicine
DUNS #
009095365
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112
Ward, Shan L; Quinn, Carson M; Steurer, Martina A et al. (2018) Variability in Pediatric Ideal Body Weight Calculation: Implications for Lung-Protective Mechanical Ventilation Strategies in Pediatric Acute Respiratory Distress Syndrome. Pediatr Crit Care Med 19:e643-e652
Kantor, David B; Petty, Carter R; Phipatanakul, Wanda et al. (2018) Transcutaneous CO-oximetry differentiates asthma exacerbation and convalescence in children. J Allergy Clin Immunol 142:676-678.e5
October, Tessie W; Dizon, Zoelle B; Roter, Debra L (2018) Is it my turn to speak? An analysis of the dialogue in the family-physician intensive care unit conference. Patient Educ Couns 101:647-652
Ciriello, Anne G; Dizon, Zoelle B; October, Tessie W (2018) Speaking a Different Language: A Qualitative Analysis Comparing Language of Palliative Care and Pediatric Intensive Care Unit Physicians. Am J Hosp Palliat Care 35:384-389
Daniels, Rodney C; Jun, Hyesun; Tiba, Hakam et al. (2018) Whole Blood Redox Potential Correlates With Progressive Accumulation of Oxygen Debt and Acts as A Marker of Resuscitation in A Swine Hemorrhagic Shock Model. Shock 49:345-351
Kantor, David B; Phipatanakul, Wanda; Hirschhorn, Joel N (2018) Gene-Environment Interactions Associated with the Severity of Acute Asthma Exacerbation in Children. Am J Respir Crit Care Med 197:545-547
Fink, Ericka L; Clark, Robert S B; Berger, Rachel P et al. (2018) 24 vs. 72 hours of hypothermia for pediatric cardiac arrest: A pilot, randomized controlled trial. Resuscitation 126:14-20
Watt, Kevin M; Avant, Debbie; Sherwin, Jennifer et al. (2018) Effect of renal function on antihypertensive drug safety and efficacy in children. Pediatr Nephrol 33:139-146
Kantor, David B; Hirshberg, Eliotte L; McDonald, Molly C et al. (2018) Fluid Balance Is Associated with Clinical Outcomes and Extravascular Lung Water in Children with Acute Asthma Exacerbation. Am J Respir Crit Care Med 197:1128-1135
Coates, Bria M; Staricha, Kelly L; Koch, Clarissa M et al. (2018) Inflammatory Monocytes Drive Influenza A Virus-Mediated Lung Injury in Juvenile Mice. J Immunol 200:2391-2404

Showing the most recent 10 out of 170 publications