UCSF and the Kaiser Division of Research (Kaiser) held a highly successful BIRCWH award from 2000 to 2005 that trained 10 Scholars in a variety of disciplines who are all currently academic faculty with successful research careers. In sum UCSF-Kaiser Scholars have published 178 scientific manuscripts, 88 as primary author and 11 in top journals. They hold 28 federal grants (10 as PI and 18 as Co-l) and 43 other grants (32 as PI and 11 as Co-l) and have 20 grants under review (17 federal and 3 other; 12 as PI and 8 as Co-l). We propose to continue and strengthen the UCSF-Kaiser BIRCWH by recruiting junior faculty Scholars with superb potential to become successful, independent translational or clinical researchers focused on chronic disease in women. We have organized our strengths in women's health into 10 Multidisciplinary Research Teams (breast cancer; cardiovascular disease; complementary and alternative medicine; dementia and cognitive dysfunction; HIV in women; menopause and hormone therapy; obesity; osteoporosis and osteoarthritis; screening for disease and urinary incontinence). Each team is lead by Senior Mentors (an experienced translational and clinical researcher) and includes Resource Faculty from multiple disciplines, Core Methodologists, extensive Research Resources and multiple Repositories of Biological Specimens or Images. Scholars will complete individualized didactic training in basic science or clinical research and practical experience mentored by senior scientists. In consultation with mentors, Scholars will prepare and annually revise a training program including a research agenda similar to NIH K-series proposals. Each plan will be built around milestones toward independence: presentations, publications and independent funding. A biweekly Core Seminar in Women's Health will cover a range of issues in women' health and a biweekly Works-in-Progress session will allow Scholars ample time for expert feedback on research projects. An Advisory Board composed of senior leaders in women's health will select Scholars, evaluate the program and advise the BIRCWH leadership. Deborah Grady, MD, MPH, Vice Chair of the Dept. of Epidemiology and Director of the UCSF Women's Health Clinical Research Center will act as PI, assisted by Drs. Steven Cummings, Emeritus Prof, of Epidemiology (Co-Pi) and Joe Selby, Director of Kaiser DOR (Co-Pi). Our goal is to create a model national resource for training successful investigators in women's health.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Physician Scientist Award (Program) (PSA) (K12)
Project #
5K12HD052163-07
Application #
7122492
Study Section
Special Emphasis Panel (ZRG1-EMNR-J (50))
Program Officer
Lamar, Charisee A
Project Start
2000-09-20
Project End
2010-07-31
Budget Start
2006-08-01
Budget End
2007-07-31
Support Year
7
Fiscal Year
2006
Total Cost
$477,057
Indirect Cost
Name
University of California San Francisco
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Rocca, Corinne H; Goodman, Suzan; Grossman, Daniel et al. (2018) Contraception after medication abortion in the United States: results from a cluster randomized trial. Am J Obstet Gynecol 218:107.e1-107.e8
Hedderson, Monique M; Brown, Susan D; Ehrlich, Samantha F et al. (2018) A Tailored Letter Based on Electronic Health Record Data Improves Gestational Weight Gain Among Women With Gestational Diabetes Mellitus: The Gestational Diabetes' Effects on Moms (GEM) Cluster-Randomized Controlled Trial. Diabetes Care 41:1370-1377
Thompson, Kirsten M J; Rocca, Corinne H; Stern, Lisa et al. (2018) Training contraceptive providers to offer intrauterine devices and implants in contraceptive care: a cluster randomized trial. Am J Obstet Gynecol 218:597.e1-597.e7
Goodman, Suzan R; El Ayadi, Alison M; Rocca, Corinne H et al. (2018) The intrauterine device as emergency contraception: how much do young women know? Contraception :
Rocca, Corinne H; Ralph, Lauren J; Wilson, Mark et al. (2018) Psychometric Evaluation of an Instrument to Measure Prospective Pregnancy Preferences: The Desire to Avoid Pregnancy Scale. Med Care :
Koss, Catherine A; Hosek, Sybil G; Bacchetti, Peter et al. (2018) Comparison of Measures of Adherence to Human Immunodeficiency Virus Preexposure Prophylaxis Among Adolescent and Young Men Who Have Sex With Men in the United States. Clin Infect Dis 66:213-219
Vafai, Yassaman; Steinberg, Julia R (2018) The effects of preabortion depressive symptoms on postabortion contraceptive effectiveness level chosen among women seeking abortions. Contraception 97:335-340
Koss, Catherine A; Ayieko, James; Mwangwa, Florence et al. (2018) Early Adopters of Human Immunodeficiency Virus Preexposure Prophylaxis in a Population-based Combination Prevention Study in Rural Kenya and Uganda. Clin Infect Dis 67:1853-1860
Moseson, Heidi; Foster, Diana Greene; Upadhyay, Ushma D et al. (2018) Contraceptive Use over Five Years After Receipt Or Denial of Abortion Services. Perspect Sex Reprod Health 50:7-14
Rocca, Corinne H; Puri, Mahesh; Shrestha, Prabhakar et al. (2018) Effectiveness and safety of early medication abortion provided in pharmacies by auxiliary nurse-midwives: A non-inferiority study in Nepal. PLoS One 13:e0191174

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