this is a multicenter, randomized double-blind, placebo controlled, parallel-group study designed to evaluate the efficacy of 0.1pg/kg rhNgf administered subcutaneously three times per week with subjects with diabetic neuropathy (symptomatic and asymptomatic and asymptomatic; type I and type ii diabetes mellitus. The study will be conducted in about 1300 patients at up to 100 centers in the united states. There will be 16 scheduled visits over a 13 month period of time. The diabetes mellitus will be kept under control with whatever medication adjustments are necessary. Certain mediacations prescribed for treatment of the peripheral neuroathy may continue while others are excluded. One may choose not to participate if the medications you wish to take are not on the allowed list.

Project Start
1997-12-01
Project End
1998-11-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
38
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Washington University
Department
Type
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
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