This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This pilot study is being done to determine the best method of characterizing head shape differences observed in individuals with sagittal synostosis and their relatives. Data collected and analyzed in this study will be used as preliminary data in a larger research proposal to identify causes of sagittal synostosis. Sagittal synostosis results in scaphocephaly, a long narrow head shape with a prominent forehead and narrow bulging occiput. In a few families, additional relatives have been diagnosed with sagittal synostosis. Some families have reported family members with long narrow heads or large foreheads, who have not been diagnosed with sagittal synostosis.
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