Abstract

This grant supports a facility where investigators from all departments of Emory University School of Medicine can study unsolved clinical problems under conditions of controlled diet and physical activity, and where most physiological and chemical variables can be monitored continuously for unlimited periods of time. Problems under study during the current year are as follows: 1. Hematology-Oncology: Hemostasis; chemotherapy of leukemia; mechanism of proteinuria in patients with neoplastic disease; protein-calorie undernutrition in cancer. 2. Cardiology: Cardiomyopathy in muscular dystrophy; effects of protein-calorie malnutrition on the heart; hypertrophic cardiomyopathy. 3. Nutrition: Prevalence, causes and treatment of protein-calorie undernutrition. 4. Neurology: Therapy of multiple sclerosis; endocrine changes in Parkinson's disease. 5. Endocrinology: Juvenile osteoporosis; diabetes insipidus; growth hormone deficiency; subclinical muscular dystrophy; Turner's syndrome; cause of growth retardation. 6. Liver Disease: Hepatorenal syndrome; gastroesophageal varices; treatment of alcoholic hepatitis; surgery for portal hypertension and intractable ascites; disorders of amino acid metabolism in cirrhosis. 7. Gastroenterology: Effects of Mg deficiency. 8. Nephrology: Mechanism of nephrolithiasis.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000039-31
Application #
3089253
Study Section
General Clinical Research Centers Committee (CLR)
Project Start
1974-10-01
Project End
1994-11-30
Budget Start
1991-01-17
Budget End
1991-11-30
Support Year
31
Fiscal Year
1991
Total Cost
Indirect Cost

  Institution

Name
Emory University
Department
Type
Schools of Medicine
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322

  Publications

Yu, Alan S L; Shen, Chengli; Landsittel, Douglas P et al. (2018) Baseline total kidney volume and the rate of kidney growth are associated with chronic kidney disease progression in Autosomal Dominant Polycystic Kidney Disease. Kidney Int 93:691-699
Stevens, Jennifer S; Reddy, Renuka; Kim, Ye Ji et al. (2018) Episodic memory after trauma exposure: Medial temporal lobe function is positively related to re-experiencing and inversely related to negative affect symptoms. Neuroimage Clin 17:650-658
Huang, Yunfeng; Hui, Qin; Walker, Douglas I et al. (2018) Untargeted metabolomics reveals multiple metabolites influencing smoking-related DNA methylation. Epigenomics 10:379-393
Nowak, Kristen L; You, Zhiying; Gitomer, Berenice et al. (2018) Overweight and Obesity Are Predictors of Progression in Early Autosomal Dominant Polycystic Kidney Disease. J Am Soc Nephrol 29:571-578
Lin, Cliff; Michopoulos, Vasiliki; Powers, Abigail et al. (2018) Affect, inflammation, and health in urban at-risk civilians. J Psychiatr Res 104:24-31
Hardy, Raven; Fani, Negar; Jovanovic, Tanja et al. (2018) Food addiction and substance addiction in women: Common clinical characteristics. Appetite 120:367-373
Askie, Lisa M; Darlow, Brian A; Finer, Neil et al. (2018) Association Between Oxygen Saturation Targeting and Death or Disability in Extremely Preterm Infants in the Neonatal Oxygenation Prospective Meta-analysis Collaboration. JAMA 319:2190-2201
Logue, Mark W; van Rooij, Sanne J H; Dennis, Emily L et al. (2018) Smaller Hippocampal Volume in Posttraumatic Stress Disorder: A Multisite ENIGMA-PGC Study: Subcortical Volumetry Results From Posttraumatic Stress Disorder Consortia. Biol Psychiatry 83:244-253
McKenzie, Katelyn A; El Ters, Mirelle; Torres, Vicente E et al. (2018) Relationship between caffeine intake and autosomal dominant polycystic kidney disease progression: a retrospective analysis using the CRISP cohort. BMC Nephrol 19:378
Dad, Taimur; Abebe, Kaleab Z; Bae, K Ty et al. (2018) Longitudinal Assessment of Left Ventricular Mass in Autosomal Dominant Polycystic Kidney Disease. Kidney Int Rep 3:619-624

Showing the most recent 10 out of 675 publications