We are studying cortisol, ACTH, and BLPH-'-endorphin secretory profiles in patients with untreated Cushing's Disease during baseline conditions and during CRH, metyrapone and dexamethasone challenge. We are testing the hypothesis that heterogeneity in the severity of depressive syndrome: mood, cognition, and sleep, is associated with heterogeneity in the profiles of cortisol and the pituitary peptides ACTH and BLPH?BE.

Project Start
1997-02-20
Project End
1997-11-30
Budget Start
1996-10-01
Budget End
1997-09-30
Support Year
37
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
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