This is a randomized study of the safety and efficacy of viracept administered with saquinavir and viracept administered with saquinavir in combination with stavudine and lamivudine in hiv positve women who have<= 1 month cumulative lifetime exposure to d4t and/or 3tc, and a plasma hiv rna measurements of at least 10,000 copies/ml. This study will also compare quantitative hiv rna levels in plasma (peripheral) with levels in vaginal secretions (genital). The last objective will be to evaluate the pharmacokinetic profile of viracept and saquirnavir.

Project Start
Project End
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
39
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Southern California
Department
Type
DUNS #
041544081
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
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