The purpose of this study is to 1) evaluate ZDV+3TC vs. d4T+ritonavir vs. ZDV+3TC+ritonavir with respect to the change in plasma HIV-1 RNA copy number from baseline to 48 weeks in stable HIV-infected children with greater or equal to 16 weeks of prior continuous antiretroviral therapy, and 2) evaluate the safety and tolerance of ZDV+3TC vs. d4T+ritonavir vs. ZDV+3TC ritonavir based upon laboratory and clinical toxicities.

Project Start
1999-12-01
Project End
2001-02-28
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
39
Fiscal Year
2000
Total Cost
$14,791
Indirect Cost
Name
University of Rochester
Department
Type
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
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