Abstract

This unit serves a facility for carrying out clinical research projects on hospitalized patients and normal subjects. Examples of projects on this unit include studies of: Hypercoagulability and Thrombosis; Growth Hormone in Pituitary Disorders; Genetic Disorders of Central Nervous System; Alcoholic Hepatitis; Bleeding Esophageal Varices; Physiology and Kinetics of Leukocytes; Intestinal Peptide Hydrolases; Chronic Active Hepatitis; Epidermolysis Bullosa; Home Intravenous Hyperalimentation; BCNU, Medrol, Procarbazine, and Radiotherapy in Treatment of Brain Tumors; Gross Peptic Esophagitis; Muco-Cutaneous Candidiasis; Bartters Syndrome; Dietary Protein, Calcium and Phosphorus; Propylthiouracil and Methimazole in Early Treatment of Hyperthroidism; Caloric Deprivation and Weight Reduction in Diabetic Control; Overnutrition and Thyroid Hormone Regulation; Adenocarcinoma Unknown Primary Evaluation; Pathogenesis of Bullosa Pemphigoid; Ectopic Hormones in Non-Endocrine Malignancy; Thyrotropin Physiology; Effects of Smoking on Codeine Disposition; Hyperbaric Oxygenation Treatments for Extracranial-Intracranial Arterial Anastomosis; Immunotherapy for Patients with Anaplastic Gliomas; Adenine Therapy for Fanconi Anemia; Clinical-Pathologic Correlation of Ocular Sarcoidosis; Acyclovir Administered to Immunocompromised Children with Varicella Zoster, Herpes Simplex and Cytomegalovirus Infections; Somatomedin-C in Acromegaly; Lymphokin Treatment of Laryngeal Papillomatosis.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000046-29
Application #
3089364
Study Section
(SRC)
Project Start
1974-10-01
Project End
1992-11-30
Budget Start
1988-12-01
Budget End
1989-11-30
Support Year
29
Fiscal Year
1989
Total Cost
Indirect Cost

  Institution

Name
University of North Carolina Chapel Hill
Department
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

Venuto, Charles S; Lim, Jihoon; Messing, Susan et al. (2018) Inflammation investigated as a source of pharmacokinetic variability of atazanavir in AIDS Clinical Trials Group protocol A5224s. Antivir Ther 23:345-351
Malinen, Melina M; Kauttonen, Antti; Beaudoin, James J et al. (2018) Novel In Vitro Method Reveals Drugs that Inhibit Solute Transporter Alpha/Beta (OST?/?). Mol Pharm :
Li, Binglan; Verma, Shefali S; Veturi, Yogasudha C et al. (2018) Evaluation of PrediXcan for prioritizing GWAS associations and predicting gene expression. Pac Symp Biocomput 23:448-459
Hanly, John G; Li, Qiuju; Su, Li et al. (2018) Cerebrovascular Events in Systemic Lupus Erythematosus: Results From an International Inception Cohort Study. Arthritis Care Res (Hoboken) 70:1478-1487
Barber, Megan R W; Hanly, John G; Su, Li et al. (2018) Economic Evaluation of Lupus Nephritis in the Systemic Lupus International Collaborating Clinics Inception Cohort Using a Multistate Model Approach. Arthritis Care Res (Hoboken) 70:1294-1302
Rini, Christine; Vu, Maihan B; Lerner, Hannah et al. (2018) A qualitative study of patient and provider perspectives on using web-based pain coping skills training to treat persistent cancer pain. Palliat Support Care 16:155-169
Little, Jayne; Parker, Ben; Lunt, Mark et al. (2018) Glucocorticoid use and factors associated with variability in this use in the Systemic Lupus International Collaborating Clinics Inception Cohort. Rheumatology (Oxford) 57:677-687
Abdullah, Lubna H; Coakley, Raymond; Webster, Megan J et al. (2018) Mucin Production and Hydration Responses to Mucopurulent Materials in Normal versus Cystic Fibrosis Airway Epithelia. Am J Respir Crit Care Med 197:481-491
Martin, Maureen P; Naranbhai, Vivek; Shea, Patrick R et al. (2018) Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1. J Clin Invest 128:1903-1912
Haas, David W; Bradford, Yuki; Verma, Anurag et al. (2018) Brain neurotransmitter transporter/receptor genomics and efavirenz central nervous system adverse events. Pharmacogenet Genomics 28:179-187

Showing the most recent 10 out of 782 publications