The purpose of this research study is to determine if FTC, given orally once daily together with other anti-HIV treatments, is equally as good as lamivudine. In the past, great progress has been made in understanding Human Immunodeficiency Virus (HIV) infection, how it leads to AIDS, and what treatments work best. Currently, the treatment recommended in US government (NIH) guidelines includes two nucleoside reverse transcriptase inhibitors (NRTI) plus a protease inhibitor (PI) or a Non-Nucleoside Reverse Transcriptase Inhibitor (NNRI). The study drug FTC is an NRTI. It is similar to the approved drug lamivudine (3TC, Epivir). This is an open-label study, which means you and the study investigator will know if you are taking FTC. This is also a randomized study, which means you will be selected by chance to either continue your current treatment or switch to a treatment that replaces lamivudine with FTC.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000046-40
Application #
6414005
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
1974-10-01
Project End
2002-11-30
Budget Start
Budget End
Support Year
40
Fiscal Year
2000
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
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