The purpose of this Phase II study is to test how well A-100, a man made form of a naturally occuring hormone called Leptin, works in controlling blood sugar levels in overweight people with type 2 diabetes and to determine how safe the drug is compared to a placebo. Leptin is made in fat cells and is believed to be involved in controlling blood sugar and body weight. A-100 may work by increasing the body's response to insulin and it may cause some weight loss. Both results would be expected to give patients better blood sugar control.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000046-40
Application #
6414082
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
1974-10-01
Project End
2002-11-30
Budget Start
Budget End
Support Year
40
Fiscal Year
2000
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
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