This is a Phase Ib safety and tolerability study of GEM-91, a 25-meroligodeoxy-nucleotide which binds to the mRNA of HIV, thus terminating translation and potentially having anti-HIV effect, 15 HIV-infected volunteers will receive GEM 91 or placebo for 14 days followed by 14 days of open label GEM 91 to assess the drugs safety, tolerability, pharmacokinetics, and anti-viral effect.

Project Start
Project End
Budget Start
Budget End
Support Year
36
Fiscal Year
1996
Total Cost
Indirect Cost
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