This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Increased calcium intake is associated with greater weight loss in animals and humans, and the weight loss is primarily loss of fat mass. Several studies in humans have also shown that calcium intake is inversely associated with body weight, that is, persons who report low calcium intake are much more likely to be overweight or obese. Studies in rats suggest that these effects may be more related to dairy intake than calcium. Alternatively, dietary calcium may exert a stronger effect than non-dairy sources of calcium. If dietary calcium intake does promote loss, than it is hypothesized that mobilization of fat and fat oxidation (i.e. the amount of fat burned) is greater on a high calcium diet. To test this, we will study humans during and after exercise after they have consumed on low- and high-dairy calcium diet for 7 days.
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